Search Result "gamma secretase and inhibitors"


In Silico Screening of Drugs to Find Potential Gamma-Secretase Inhibitors Using Pharmacophore Modeling, QSAR and Molecular Docking Studies

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 9 Year: 2014 Page: 770-780
Author(s): Arun Ekiri Vaidyanathan Raman,Karthic Krishnan,Arun Maurya,Nandini Sarkar

Review of Synthesis, Assay, and Prediction of β and γ-secretase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 8 Year: 2012 Page: 828-844
Author(s): Helena Nino,Jose Enrique Rodriguez-Borges,Xerardo Garcia-Mera,Francisco Prado-Prado

The Search for γ-Secretase and Development of Inhibitors

Journal: Current Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2002 Page: 1087-1106
Author(s): Jui-Yi Tsai, Michael S. Wolfe, Weiming Xia

Research Article

Identification of High-affinity Small Molecules Targeting Gamma Secretase for the Treatment of Alzheimer’s Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 13 Year: 2019 Page: 1173-1187
Author(s): Meer Asif Ali,Sugunakar Vuree,Himshikha Goud,Tajamul Hussain,Anuraj Nayarisseri,Sanjeev Kumar Singh

Computer-Aided Drug Design Applied to Beta and Gamma Secretase Inhibitors-Perspectives for New Alzheimer Disease Therapy

Journal: Current Enzyme Inhibition
Volume: 2 Issue: 4 Year: 2006 Page: 311-328
Author(s): Speranta Avram, Adina L. Milac, Dan F. Mihailescu, Aurelia Dabu, Maria L. Flonta

Gamma-Secretase as a Pharmacological Target in Alzheimer Disease Research: When, Why and How?

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 3 Year: 2006 Page: 4313-4335
Author(s): Chewki Ziani-Cherif, Bachir Mostefa-Kara, Fatima Z. Brixi-Gormat

Review Article

Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia

Journal: Current Drug Targets
Volume: 22 Issue: 15 Year: 2021 Page: 1789-1798
Author(s): Bhupendra Kaushik,Dilipkumar Pal,Supriyo Saha

Discovery of Notch-Sparing γ-Secretase Inhibitors

Journal: Current Alzheimer Research
Volume: 7 Issue: 3 Year: 2010 Page: 207-209
Author(s): C.E. Augelli-Szafran, H.-X. Wei, D. Lu, J. Zhang, Y. Gu, T. Yang, P. Osenkowski, W. Ye, M.S. Wolfe

Recent Progress in the Medicinal Chemistry of γ-Secretase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 17-33
Author(s): Richard E. Olson, Charles F. Albright

Views on Amyloid Hypothesis and Secretase Inhibitors for Treating Alzheimers Disease: Progress and Problems

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 3 Year: 2006 Page: 4295-4312
Author(s): Jeffrey-Tri Nguyen, Abdellah Yamani, Yoshiaki Kiso

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