Search Result "allos-teric indole site"


QSAR and Molecular Modeling Studies on a Series of Indole-based Pyridone Analogues as HCV NS5B Polymerase Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 13 Issue: 8 Year: 2016 Page: 757-770
Author(s): Neelu Singh, Basheerulla Shaik, Neeraj Agrawal, Anita K, Vijay K. Agrawal, Satya P. Gupta

Research Article

Synthesis, Molecular Docking and Biological Evaluation of Novel Flavone Derivatives as Potential Anticancer Agents Targeting Akt

Journal: Medicinal Chemistry
Volume: 17 Issue: 2 Year: 2021 Page: 158-170
Author(s): Heba M. Abo-Salem,Abdullah A Gibriel,Mohamed E. El Awady,Adel H. Mandour

Physiological Control of Liver Glycogen Metabolism: Lessons from Novel Glycogen Phosphorylase Inhibitors

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1175-1187
Author(s): L. Agius

Structural Analysis and Comparison of Active Site Architecture from Ancient Bacteria to Human Phosphatases: A Novel Approach to Identification of Lead Compounds with Increased Specificity and Potency for Drug Discovery

Journal: Current Physical Chemistry
Volume: 5 Issue: 3 Year: 2015 Page: 195-205
Author(s): Gemma Topaz, Dumazo Ngesina, Lunecee Eligene, Davin Watson, Kimberly A. Stieglitz

Review Article

Displacement of Drugs from Human Serum Albumin: From Molecular Interactions to Clinical Significance

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 18 Year: 2017 Page: 1930-1947
Author(s): Hrvoje Rimac,Željko Debeljak,Mirza Bojić,Larisa Miller

The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 14-25
Author(s): Brian D. Hudson, Trond Ulven, Graeme Milligan

Recent Advances in the Allosteric Inhibition of Glycogen Phosphorylase

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1139-1155
Author(s): W. A. Loughlin

A Hydrazide Linker Strategy for Heterobivalent Compounds as Ortho- and Allosteric Ligands of Acetylcholine-Binding Proteins

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 2 Year: 2011 Page: 2731-2748
Author(s): Paul W. Elsinghorst, Wolfgang Hartig, Daniela Gundisch, Klaus Mohr, Christian Trankle, Michael Gutschow

Desformylflustrabromine: A Novel Positive Allosteric Modulator for beta2 Subunit Containing Nicotinic Receptor Sub-Types

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 14 Year: 2016 Page: 2057-2063
Author(s): Anshul A. Pandya

Fragment Based Strategies for Discovery of Novel HIV-1 Reverse Transcriptase and Integrase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 1 Year: 2016 Page: 1135-1153
Author(s): Catherine F. Latham, Jennifer La, Ricky N. Tinetti, David K. Chalmers, Gilda Tachedjian

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