Search Result "active site mapping"


Mapping of the Active Site of Proteases in the 1960s and Rational Design of Inhibitors/Drugs in the 1990s

Journal: Current Protein & Peptide Science
Volume: 6 Issue: 6 Year: 2005 Page: 501-512
Author(s): I. Schechter

Mapping of the Benzodiazepine Recognition Site on GABA-A Receptors

Journal: Current Topics in Medicinal Chemistry
Volume: 2 Issue: 8 Year: 2002 Page: 833-839
Author(s): Erwin Sigel

An Expanded, Unified Substrate Recognition Site Map for Mammalian Cytochrome P450s: Analysis of Molecular Interactions Between 15 Mammalian CYP450 Isoforms and 868 Substrates

Journal: Current Drug Metabolism
Volume: 12 Issue: 7 Year: 2011 Page: 684-700
Author(s): Alexander Zawaira, Lim Yen Ching, Lauren Coulson, Jonathan Blackburn, Yap Chun Wei

A Theoretical Investigation on the Pleiotropic Effects of Statins as p38 MAP Kinase Ligands

Journal: Letters in Drug Design & Discovery
Volume: 7 Issue: 8 Year: 2010 Page: 546-550
Author(s): Carla M.S. Menezes, Carolina M. Avila, Eliezer J. Barreiro

Mapping Selectivity and Specificity of Active Site of Plasmepsins from Plasmodium falciparum Using Molecular Interaction Field Approach

Journal: Protein & Peptide Letters
Volume: 14 Issue: 6 Year: 2007 Page: 569-574
Author(s): Amit Kumar, Indira Ghosh

Mitogen Activated Protein (MAP) Kinases: Development of ATP and Non- ATP Dependent Inhibitors

Journal: Medicinal Chemistry
Volume: 2 Issue: 2 Year: 2006 Page: 213-222
Author(s): Chad N. Hancock, Alba T. Macias, Alexander D. MacKerell, Jr., Paul Shapiro

Computational Insights for the Discovery of Non-ATP Competitive Inhibitors of MAP Kinases

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 9 Year: 2012 Page: 1173-1185
Author(s): Michael J. Schnieders, Tamer S. Kaoud, Chunli Yan, Kevin N. Dalby, Pengyu Ren

Recent Developments of p38α MAP Kinase Inhibitors as Antiinflammatory Agents Based on the Imidazole Scaffolds

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 1 Year: 2013 Page: 1997-2016
Author(s): Ting-Ting Kong, Cheng-Mei Zhang, Zhao-Peng Liu

Mapping Protein: Carbohydrate Interactions

Journal: Current Protein & Peptide Science
Volume: 4 Issue: 1 Year: 2003 Page: 11-20
Author(s): Gerald F. Audette, Louis T.J. Delbaere, Jim Xiang

Malleability and Versatility of Cytochrome P450 Active Sites Studied by Molecular Simulations

Journal: Current Drug Metabolism
Volume: 13 Issue: 2 Year: 2012 Page: 190-196
Author(s): Chris Oostenbrink, Anita de Ruiter, Jozef Hritz, Nico Vermeulen

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