Search Result "PBPK modeling"


Development of a PBPK Model for Monoclonal Antibodies and Simulation of Human and Mice PBPK of a Radiolabelled Monoclonal Antibody

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 9 Year: 2009 Page: 988-1007
Author(s): Tomi Heiskanen, Tomas Heiskanen, Kalevi Kairemo

PBPK Modeling of Intestinal and Liver Enzymes and Transporters in Drug Absorption and Sequential Metabolism

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 743-761
Author(s): Jianghong Fan, Shu Chen, Edwin C.Y. Chow, K. Sandy Pang

Systematic Review Article

PBPK Modeling as an Alternative Method of Interspecies Extrapolationthat Reduces the Use of Animals: A Systematic Review

Journal: Current Medicinal Chemistry
Volume: 31 Issue: 1 Year: 2024 Page: 102-126
Author(s): Karen Dayana Lancheros Porras,Izabel Almeida Alves,Diana Marcela Aragón Novoa

Why We Need Proper PBPK Models to Examine Intestine and Liver Oral Drug Absorption

Journal: Current Drug Metabolism
Volume: 14 Issue: 1 Year: 2013 Page: 57-79
Author(s): Edwin C.Y. Chow,K. Sandy Pang

Research Article

The Development of a Physiologically Based Pharmacokinetic (PBPK) Model ofAndrographolide in Mice and Scaling it up to Rats, Dogs, and Humans

Journal: Current Drug Metabolism
Volume: 23 Issue: 7 Year: 2022 Page: 538-552
Author(s):

Review Article

PBPK in Preterm and Term Neonates: A Review

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 38 Year: 2017 Page: 5943-5954
Author(s): Robin Michelet,Jan Van Bocxlaer,An Vermeulen

Research Article

Using PBPK Modeling to Predict Drug Exposure and Support Dosage Adjustments in Patients With Renal Impairment: An Example with Lamivudine

Journal: Current Drug Discovery Technologies
Volume: 17 Issue: 3 Year: 2020 Page: 387-396
Author(s): Kushal Shah,Briann Fischetti,Agnes Cha,David R. Taft

Review Article

Physiologically-based Pharmacokinetic (PBPK) Modelling of Transporter Mediated Drug Absorption, Clearance and Drug-drug Interactions

Journal: Current Drug Metabolism
Volume: 22 Issue: 7 Year: 2021 Page: 523-531
Author(s): Kunal S. Taskar,Isobel Harada,Ravindra V. Alluri

Research Article

Application of a “Fit for Purpose” PBPK Model to Investigate the CYP3A4 Induction Potential of Enzalutamide

Journal: Drug Metabolism Letters
Volume: 10 Issue: 3 Year: 2016 Page: 172-179
Author(s): Rangaraj Narayanan,Matthew Hoffmann,Gondi Kumar,Sekhar Surapaneni

Review Article

PBPK Modeling - A Predictive, Eco-Friendly, Bio-Waiver Tool for Drug Research

Journal: Current Drug Discovery Technologies
Volume: 14 Issue: 3 Year: 2017 Page: 142-155
Author(s): Baishakhi De,Koushik Bhandari,Ranjan Mukherjee,Prakash Katakam,Shanta K. Adiki,Rohit Gundamaraju,Analava Mitra

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