Search Result "Mechanism based inactivation (MBI)"
Prediction of Drug-Drug Interactions Arising From Mechanism-Based Inactivation: Key Input Parameters and Impact on Risk Assessment
Journal: Current Drug Metabolism
Volume: 12 Issue: 9 Year: 2011 Page: 871-890
Author(s): Simon G. Wong
Drug-Drug Interactions via Mechanism-Based Cytochrome P450 Inactivation: Points to Consider for Risk Assessment from In Vitro Data and Clinical Pharmacologic Evaluation
Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 449-462
Author(s): Karthik Venkatakrishnan, R. Scott Obach
Integrating In Vitro Kinetic Data from Compounds Exhibiting Induction, Reversible Inhibition and Mechanism-Based Inactivation: In Vitro Study Design
Journal: Current Drug Metabolism
Volume: 5 Issue: 2 Year: 2004 Page: 141-146
Author(s): Donavon J. McConn, Zhiyang Zhao
Mechanism-Based Inactivators as Probes of Cytochrome P450 Structure and Function
Journal: Current Drug Metabolism
Volume: 2 Issue: 3 Year: 2001 Page: 215-243
Author(s): Ute M. Kent, Monica I. Jushchhyshyn, Paul F. Hollenberg
Assessment of the Inactivation Potential of Desethylamiodarone on Human CYP1A1
Journal: Drug Metabolism Letters
Volume: 4 Issue: 1 Year: 2010 Page: 9-14
Author(s): Marwa E. Elsherbiny, Ayman O.S. El-Kadi, Dion R. Brocks
Mechanism-Based Inhibitors from Phytomedicine: Risks of Hepatotoxicity and their Potential Hepatotoxic Substructures
Journal: Current Drug Metabolism
Volume: 17 Issue: 10 Year: 2016 Page: 971-991
Author(s): Lili Wang,Xin He,Chunhuan Jin,Gregory Ondieki
Enzyme Kinetics for Clinically Relevant CYP Inhibition
Journal: Current Drug Metabolism
Volume: 6 Issue: 3 Year: 2005 Page: 241-257
Author(s): Zhi-Yi Zhang, Y. Nancy Wong
Assessment of Cytochrome P450 Enzyme Inhibition and Inactivation in Drug Discovery and Development
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 382-403
Author(s): David O. Nettleton, Heidi J. Einolf
Cytochrome P450 Turnover: Regulation of Synthesis and Degradation, Methods for Determining Rates, and Implications for the Prediction of Drug Interactions
Journal: Current Drug Metabolism
Volume: 9 Issue: 5 Year: 2008 Page: 384-393
Author(s): Jiansong Yang, Mingxiang Liao, Magang Shou, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker, Amin Rostami-Hodjegan
Inactivation of CYP3A4 by Benzbromarone in Human Liver Microsomes
Journal: Drug Metabolism Letters
Volume: 10 Issue: 1 Year: 2016 Page: 16-21
Author(s): Yasuhiro Masubuchi,Shinji Kondo