Search Result "IC50 or EC50"


Sensitivity of SARS/MERS CoV to Interferons and Other Drugs Based on Achievable Serum Concentrations in Humans

Journal: Infectious Disorders - Drug Targets
Volume: 14 Issue: 1 Year: 2014 Page: 37-43
Author(s): David R. Strayer,Robert Dickey,William A. Carter

Compound Ranking Based on a New Mathematical Measure of Effectiveness Using Time Course Data from Cell-Based Assays

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 16 Issue: 3 Year: 2013 Page: 168-179
Author(s): Francisco J. Diaz,Peter R. McDonald,Anuradha Roy,Byron Taylor,Ashleigh Price,Jessica Hall,Brian S.J. Blagg,Rathnam Chaguturu

Design, Synthesis and Biological Testing of Cyclohexenone Derivatives of Combretastatin-A4

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 2 Year: 2007 Page: 144-148
Author(s): Jennifer Ruprich, Andrew Prout, John Dickson, Brent Younglove, Lawrence Nolan, Khyati Baxi, Regan LeBlanc, Lori Forrest, Patrice Hills, Herman Holt Jr, Hilary Mackay, Toni Brown, Susan L. Mooberry, Moses Lee

Presentation of the β -Carboxamidophosphonate Arrangement in Substrate Structures Targeting HIV-1 PR

Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 2 Year: 2009 Page: 139-145
Author(s): N. J. Wardle, H. R. Hudson, R. W. Matthews, C. Nunn, C. Vella, S.W. A. Bligh

Research Article

Design, Synthesis, and Docking Studies of Thioimidazolyl DiketoacidDerivatives Targeting HIV-1 Integrase

Journal: Medicinal Chemistry
Volume: 18 Issue: 5 Year: 2022 Page: 616-628
Author(s): Afshin Zarghi,Zahra Hajimahdi,Rouhollah Vahabpour Roudsari,Nafiseh Karimi

Research Article

High Antioxidant Capacities and Anti-inflammatory Effects of Hammada elegans Botsch. Extracts: An in vitro Assessment

Journal: Current Enzyme Inhibition
Volume: 15 Issue: 1 Year: 2019 Page: 55-68
Author(s): Bensafiddine Feriha,Asseli Brahim,Mahfoudi Reguia,Djeridane Amar,Yousfi Mohamed

Research Article

First Total Synthesis of ω-Phenyl Δ6 Fatty Acids and their Leishmanicidal and Anticancer Properties

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 5 Year: 2018 Page: 418-427
Author(s): Nestor M. Carballeira,Christian Morales-Guzman,Ester Alvarez-Benedicto,Zally Torres-Martinez,Yamixa Delgado,Kai H. Griebenow,Arthur D. Tinoco,Rosa M. Reguera,Yolanda Perez-Pertejo,Ruben Carbajo-Andres,Rafael Balana-Fouce

Synthesis and HIV-1 Inhibitory Activities of Dicaffeoyl and Digalloyl Esters of Quinic Acid Derivatives

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 5 Year: 2013 Page: 724-733
Author(s): C. O.R. Junior, S. C. Verde, C. A.M. Rezende, W. Caneschi, M. R.C. Couri, B. R. McDougall, W. E. Robinson, Jr., M. V. de Almeida

Calcium Level Controlling Activities of Novel Derivatives of Amlodipine,Riodipine and Cerebrocrast

Journal: Letters in Drug Design & Discovery
Volume: 9 Issue: 3 Year: 2012 Page: 322-328
Author(s): R. Vilskersts, B. Vigante, Z. Neidere, A. Krauze, I. Domracheva, L. Bekere, I. Shestakova, G. Duburs, M. Dambrova

2-Hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylic Acid with Inbuilt β-N-Hydroxy-γ-keto-acid Pharmacophore as HCV NS5B Polymerase Inhibitors

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 4 Year: 2012 Page: 613-624
Author(s): R. R. Deore, G. S. Chen, C. -S. Chen, P. -T. Chang, M. -H. Chuang, T. -R. Chern, H. -C. Wang, J. -W. Chern

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