Search Result "FLIPR Assay"


Identification and Characterization of mGlu3 Ligands Using a High Throughput FLIPR Assay for Detection of Agonists, Antagonists, and Allosteric Modulators

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 7 Year: 2011 Page: 631-641
Author(s): Steven D. Pratt, Mario Mezler, Herve Geneste, Margot H.M. Bakker, Philip J. Hajduk, Sujatha M. Gopalakrishnan

Development of a Novel High-Throughput Assay for the Investigation of GlyT-1b Neurotransmitter Transporter Function

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 1 Year: 2006 Page: 9-14
Author(s): Lynda Allan, J. L. Leith, Marianthi Papakosta, John A. Morrow, Nicholas G. Irving, Brian W. McFerran, Alan G. Clark

Development and Validation of a Fluorescence-Based HTS Assay for the Identification of P/Q-Type Calcium Channel Blockers

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 15 Issue: 5 Year: 2012 Page: 372-385
Author(s): Mario Mezler,David Hermann,Andrew M. Swensen,Andreas Draguhn,Georg C. Terstappen,Gerhard Gross,Hans Schoemaker,Gail Freiberg,Steve Pratt,Sujatha M. Gopalakrishnan,Volker Nimmrich

Chimeric and Promiscuous G Proteins in Drug Discovery and the Deorphanization of GPCRs

Journal: Drug Design Reviews - Online (Discontinued)
Volume: 2 Issue: 1 Year: 2005 Page: 66-79
Author(s): David C. New, Yung H. Wong

Measuring Intracellular Calcium Fluxes in High Throughput Mode

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 4 Year: 2003 Page: 355-362
Author(s): Chris Chambers, Fiona Smith, Christine Williams, Sandra Marcos, Zhen Han Liu, Paul Hayter, Giuseppe Ciaramella, Wilma Keighley, Phil Gribbon, Andreas Sewing

Functional Cell-Based Assays in Microliter Volumes for Ultra-High Throughput Screening

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 7 Year: 2008 Page: 495-504
Author(s): Frank Wunder, Bernd Kalthof, Thomas Muller, Jorg Huser

Label-Free Cell-Based Assays for GPCR Screening

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 5 Year: 2008 Page: 357-369
Author(s): Ye Fang, Anthony G. Frutos, Ronald Verklereen

Profiling of Multiple Signal Pathway Activities by Multiplexing Antibody and GFP-Based Translocation Assays

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 7 Year: 2008 Page: 537-544
Author(s): Ulla Henriksen, Jacob Fog, Frosty Loechel, Morten Praestegaard

Integrative Functional Assays, Chemical Genomics and High Throughput Screening: Harnessing Signal Transduction Pathways to a Common HTS Readout

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 1 Year: 2006 Page: 1717-1729
Author(s): Ethan S. Burstein, Fabrice Piu, Jian-Nong Ma, Jacques T. Weissman, Erika A. Currier, Norman R. Nash, David M. Weiner, Tracy A. Spalding, Hans H. Schiffer, Andria L. Del Tredici, Mark R. Brann

Application of Affinity Selection-Mass Spectrometry Assays to Purification and Affinity-Based Screening of the Chemokine Receptor CXCR4

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 15 Issue: 6 Year: 2012 Page: 473-485
Author(s): Charles E. Whitehurst,Zhiping Yao,Denise Murphy,Mingxuan Zhang,Shane Taremi,Lisa Wojcik,Julie M. Strizki,Jack D. Bracken,Cliff C. Cheng,Xianshu Yang,Gerald W. Shipps,Michael Ziebell,Elliott Nickbarg

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