Search Result "Enzyme inactivation by oxidation"


Assessment of Cytochrome P450 Enzyme Inhibition and Inactivation in Drug Discovery and Development

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 382-403
Author(s): David O. Nettleton, Heidi J. Einolf

High Throughput Quantitative Assessment of CYP Inactivation Using 2 Concentration Points

Journal: Drug Metabolism Letters
Volume: 3 Issue: 2 Year: 2009 Page: 78-82
Author(s): Daniel Albaugh, Thomas Farrell, Michael Langan, W. George Lai

Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Chemical Mechanisms, Structure-Activity Relationships and Relationship to Clinical Drug-Drug Interactions and Idiosyncratic Adverse Drug Reactions

Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 407-447
Author(s): Amit S. Kalgutkar, R. Scott Obach, Tristan S. Maurer

Molecular Analysis and Modeling of Inactivation of Human CYP2D6 by Four Mechanism Based Inactivators

Journal: Drug Metabolism Letters
Volume: 6 Issue: 1 Year: 2012 Page: 7-14
Author(s): Mara Livezey, Leslie D. Nagy, Laura E. Diffenderfer, Evan J. Arthur, David J. Hsi, Jeffrey M. Holton, Laura Lowe Furge

Photodynamic Inactivation of Bacteria

Journal: Current Bioactive Compounds
Volume: 2 Issue: 2 Year: 2006 Page: 127-142
Author(s): Edgardo N. Durantini

Assessment of the Inactivation Potential of Desethylamiodarone on Human CYP1A1

Journal: Drug Metabolism Letters
Volume: 4 Issue: 1 Year: 2010 Page: 9-14
Author(s): Marwa E. Elsherbiny, Ayman O.S. El-Kadi, Dion R. Brocks

Advances in the Development of Inactivated Virus Vaccines

Journal: Recent Patents on Anti-Infective Drug Discovery
Volume: 1 Issue: 3 Year: 2006 Page: 291-296
Author(s): Fausto Stauffer, Tatiana El-Bacha, Andrea T. Da Poian

Novel Agents Targeting Nitric Oxide

Journal: Current Vascular Pharmacology
Volume: 10 Issue: 1 Year: 2012 Page: 61-76
Author(s): Anna-Maria Kampoli, Dimitris Tousoulis, Costas Tentolouris, Christodoulos Stefanadis

Selective Modifications of Steroids Performed by Oxidative Enzymes

Journal: Current Organic Chemistry
Volume: 16 Issue: 21 Year: 2012 Page: 2551-2582
Author(s): Alina Swizdor,Teresa Kolek,Anna Panek,Natalia Milecka

The Molecular Mechanism of MAPK / ERK Inactivation

Journal: Current Genomics
Volume: 5 Issue: 4 Year: 2004 Page: 385-393
Author(s): Zhong Yao, Rony Seger

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