Search Result "DRUG INACTIVATION"


Assessment of Cytochrome P450 Enzyme Inhibition and Inactivation in Drug Discovery and Development

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 382-403
Author(s): David O. Nettleton, Heidi J. Einolf

Molecular Analysis and Modeling of Inactivation of Human CYP2D6 by Four Mechanism Based Inactivators

Journal: Drug Metabolism Letters
Volume: 6 Issue: 1 Year: 2012 Page: 7-14
Author(s): Mara Livezey, Leslie D. Nagy, Laura E. Diffenderfer, Evan J. Arthur, David J. Hsi, Jeffrey M. Holton, Laura Lowe Furge

Prediction of Drug-Drug Interactions Arising From Mechanism-Based Inactivation: Key Input Parameters and Impact on Risk Assessment

Journal: Current Drug Metabolism
Volume: 12 Issue: 9 Year: 2011 Page: 871-890
Author(s): Simon G. Wong

High Throughput Quantitative Assessment of CYP Inactivation Using 2 Concentration Points

Journal: Drug Metabolism Letters
Volume: 3 Issue: 2 Year: 2009 Page: 78-82
Author(s): Daniel Albaugh, Thomas Farrell, Michael Langan, W. George Lai

Mechanism-Based Inactivation of Cytochrome P450 Enzymes: Chemical Mechanisms, Structure-Activity Relationships and Relationship to Clinical Drug-Drug Interactions and Idiosyncratic Adverse Drug Reactions

Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 407-447
Author(s): Amit S. Kalgutkar, R. Scott Obach, Tristan S. Maurer

The Structure of Ribosome Inactivating Proteins

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 4 Issue: 5 Year: 2004 Page: 477-486
Author(s): Jon D. Robertus, Arthur F. Monzingo

Photodynamic Inactivation of Bacteria

Journal: Current Bioactive Compounds
Volume: 2 Issue: 2 Year: 2006 Page: 127-142
Author(s): Edgardo N. Durantini

Advances in the Development of Inactivated Virus Vaccines

Journal: Recent Patents on Anti-Infective Drug Discovery
Volume: 1 Issue: 3 Year: 2006 Page: 291-296
Author(s): Fausto Stauffer, Tatiana El-Bacha, Andrea T. Da Poian

Assessment of the Inactivation Potential of Desethylamiodarone on Human CYP1A1

Journal: Drug Metabolism Letters
Volume: 4 Issue: 1 Year: 2010 Page: 9-14
Author(s): Marwa E. Elsherbiny, Ayman O.S. El-Kadi, Dion R. Brocks

Cytotoxicity and Toxicity to Animals and Humans of Ribosome-Inactivating Proteins

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 4 Issue: 5 Year: 2004 Page: 513-521
Author(s): Maria Giulia Battelli

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