Search Result "undruggable sites"
Protein-Protein Interaction Inhibition (2P2I): Fewer and Fewer Undruggable Targets
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 1 Year: 2009 Page: 968-983
Author(s): Stephane Betzi, Francoise Guerlesquin, Xavier Morelli
Exploring the Lapse in Druggability: Sequence Analysis, Structural Dynamics and Binding Site Characterization of K-RasG12C Variant, a Feasible Oncotherapeutics Target
Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 11 Year: 2018 Page: 1540-1550
Author(s): Emmanuel A. Adeniji,Fisayo A. Olotu,Mahmoud E.S. Soliman
Peptide-based PROTACs: Current Challenges and FuturePerspectives
Journal: Current Medicinal Chemistry
Volume: 31 Issue: 2 Year: 2024 Page: 208-222
Author(s):
Drug Discovery and Protein Tyrosine Phosphatases
Journal: Current Medicinal Chemistry
Volume: 16 Issue: 1 Year: 2009 Page: 2095-2176
Author(s): Mark A.T. Blaskovich
The Dark Side of Protein Kinase CK2 Inhibition
Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2867-2884
Author(s): G. Cozza, F. Meggio, S. Moro
Facile Synthesis of Boc-Protected Selenocystine and its Compatibility with Late-Stage Farnesylation at Cysteine Site
Journal: Protein & Peptide Letters
Volume: 28 Issue: 6 Year: 2021 Page: 603-611
Author(s): Peng-Cheng Zhu,Yong-Xiang Chen
PROTAC: A Novel Drug Delivery Technology for Targeting Proteins inCancer Cells
Journal: Current Drug Discovery Technologies
Volume: 20 Issue: 2 Year: 2023 Page: 63-73
Author(s): Rakesh Kumar Sindhu,Shantanu Kumar Yadav
Lipid-based siRNA Delivery Systems: Challenges, Promises and Solutions Along the Long Journey
Journal: Current Pharmaceutical Biotechnology
Volume: 17 Issue: 8 Year: 2016 Page: 728-740
Author(s): Can Sarisozen,Giuseppina Salzano,Vladimir P. Torchilin
Key Aspects of the Novartis Compound Collection Enhancement Project for the Compilation of a Comprehensive Chemogenomics Drug Discovery Screening Collection
Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 4 Year: 2005 Page: 397-411
Author(s): Edgar Jacoby, Ansgar Schuffenhauer, Maxim Popov, Kamal Azzaoui, Benjamin Havill, Ulrich Schopfer, Caroline Engeloch, Jaroslav Stanek, Pierre Acklin, Pascal Rigollier, Friederike Stoll, Guido Koch, Peter Meier, David Orain, Rudolph Giger, Jurgen Hinrichs, Karine Malagu, Jurg Zimmermann, Hans- Joerg Roth
Structure-based Druggability Assessment of Anti-virulence Targets from Pseudomonas aeruginosa
Journal: Current Protein & Peptide Science
Volume: 20 Issue: 1 Year: 2019 Page: 1189-1203
Author(s): Thamires Q. Froes,Regina L. Baldini,Sandor Vajda,Marcelo S. Castilho