Search Result "lipinski`s rule."


Research Article

Analysis of the Applicability and Use of Lipinski`s Rule for Central Nervous System Drugs

Journal: Letters in Drug Design & Discovery
Volume: 13 Issue: 1 Year: 2016 Page: 999-1006
Author(s): Thais B. Fernandes, Mariana C. F. Segretti, Michelle C. Polli, Roberto Parise-Filho

Lipinski’s Rule of Five

Ebook: 2-Deoxy-D-Glucose: Chemistry and Biology
Volume: 1 Year: 2024
Author(s):
Doi: 10.2174/9789815305159124010015

Research Article

New SARS-CoV-2 Mpro Inhibitor by Ascorbic Acid: Design, MolecularDocking, Lipinski’s Rule and ADMET Analysis

Journal: Coronaviruses
Volume: 5 Issue: 1 Year: 2024 Page: 13-52
Author(s): Abdulrahman Salman Alazmi

Research Article

Withania somnifera Phytochemicals Confer Neuroprotection by Inhibition of the Catalytic Domain of Human Matrix Metalloproteinase-9

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 6 Year: 2017 Page: 718-726
Author(s): Gaurav Kumar,Pankaj Paliwal,Ranjana Patnaik

Review Article

Description and In silico ADME Studies of US-FDA Approved Drugs orDrugs under Clinical Trial which Violate the Lipinski’s Rule of 5

Journal: Letters in Drug Design & Discovery
Volume: 21 Issue: 8 Year: 2024 Page: 1334-1358
Author(s): Ankit Kumar Singh,Jagat Pal Yadav

Research Article

Synthesis, In silico Molecular Docking and Pharmacokinetic Studies, In vitro Antimycobacterial and Antimicrobial Studies of New Imidozolones Clubbed with Thiazolidinedione

Journal: Current Computer-Aided Drug Design
Volume: 14 Issue: 4 Year: 2018 Page: 269-283
Author(s): Imran. H. Khan,Navin B. Patel,Vatsal M. Patel

General Research Article

Structure-based Virtual Screening, Molecular Docking, MolecularDynamics Simulation, and Metabolic Reactivity Studies ofQuinazoline Derivatives for their Anti-EGFR Activity AgainstTumor Angiogenesis

Journal: Current Medicinal Chemistry
Volume: 31 Issue: 5 Year: 2024 Page: 595-619
Author(s): Altaf Ahmad Shah,Manoj Kumar Yadav,Mohammad Amjad Kamal

Research Article

Exploration of Novel PDEδ Inhibitor Based on Pharmacophore andMolecular Docking against KRAS Mutant in Colorectal Cancer

Journal: Current Drug Discovery Technologies
Volume: 20 Issue: 4 Year: 2023 Page: 63-72
Author(s):

Research Article

Antihelminthic Activity of Some 2-Substituted Thieno[2,3-d]pyrimidin-4-ones

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 8 Year: 2018 Page: 887-894
Author(s): Anelia Mavrova,Stefan Dimov,Dimitar Vuchev,Kameliya Anichina,Denitsa Yancheva

Novel Rule-Based Method for Multi-Parametric Multi-Objective Decision Support in Lead Optimization Using KEM

Journal: Current Computer-Aided Drug Design
Volume: 4 Issue: 1 Year: 2008 Page: 35-45
Author(s): Mohammad Afshar, Nathalie Jullian

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