Search Result "Pim-1 kinase."


Research Article

Identification of Pim-1 Kinase Inhibitors by Pharmacophore Model, MolecularDocking-based Virtual Screening, and Biological Evaluation

Journal: Current Computer-Aided Drug Design
Volume: 18 Issue: 3 Year: 2022 Page: 240-246
Author(s):

New Potent and Selective Inhibitor of Pim-1/3 Protein Kinases Sensitizes Human Colon Carcinoma Cells to Doxorubicin

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 9 Year: 2014 Page: 1228-1236
Author(s): Pascale Moreau,Lyubov G. Dezhenkova,Fabrice Anizon,Lionel Nauton,Vincent Thery,Shuguang Liang,Dmitry N. Kaluzhny,Alexander A. Shtil

Research Article

Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim-1 Kinase Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 12 Year: 2018 Page: 1711-1728
Author(s): Mahmoud A. Abdelaziz Mahmoud,Rafat M. Mohareb,Meshari. A. Al-Sharif

Review Article

Signal Transduction through JAK-STAT and NF-κB Regulated Pim-1 Kinase: Novel Target for Anticancer Leads

Journal: Current Signal Transduction Therapy
Volume: 13 Issue: 2 Year: 2018 Page: 83-104
Author(s): Sisir Nandi,Mohd Salman,Ankita Sharma,Mohit Kumar

Research Article

New Mechanistic Insight on the PIM-1 Kinase Inhibitor AZD1208 Using Multidrug Resistant Human Erythroleukemia Cell Lines and Molecular Docking Simulations

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 11 Year: 2019 Page: 914-926
Author(s): Maiara Bernardes Marques,Michael González-Durruthy,Bruna Félix da Silva Nornberg,Bruno Rodrigues Oliveira,Daniela Volcan Almeida,Ana Paula de Souza Votto,Luis Fernando Marins

The Pim Kinases: New Targets for Drug Development

Journal: Current Drug Targets
Volume: 12 Issue: 1 Year: 2011 Page: 2059-2066
Author(s): Ronan Swords, Kevin Kelly, Jennifer Carew, Stefan Nawrocki, Devalingam Mahalingam, John Sarantopoulos, David Bearss, Francis Giles

Research Article

Synthesis of Tetrahydrobenzo[b]thiophene-3-carbohydrazide Derivatives as Potential Anti-cancer Agents and Pim-1 Kinase Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 19 Issue: 1 Year: 2019 Page: 1737-1753
Author(s): Rafat Milad Mohareb,Wagnat Wahba Wardakhan,Nermeen Saeed Abbas

Research Article

The Uses of Dimedone for the Synthesis of Thiophene, Thiazole and Annulated Derivatives with Antitumor, Pim-1 Kinase Inhibitions, PAINS Evaluations and Molecular Docking

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 16 Year: 2021 Page: 2258-2277
Author(s): Wagnat W. Wardakhan,Amira M. Elmetwally,Abeer A. Mohamed,Rafat M. Mohareb

Research Article

New Approaches for the Synthesis of Heterocyclic Compounds Corporating Benzo[d]imidazole as Anticancer Agents, Tyrosine, Pim-1 Kinases Inhibitions and their PAINS Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 3 Year: 2021 Page: 327-342
Author(s): Rafat M. Mohareb,Yara R. Milad,Bahaa M. Mostafa,Reem A. El-Ansary

Density Functional Theory, Docking, Bioisosteric Replacement, Pharmacophore Perception, Physical Chemical Analyses of the Interactions of Novel PIM-1 Inhibitors with Suitable Pharmacokinetic Properties for Cancer Treatment

Journal: Current Physical Chemistry
Volume: 3 Issue: 4 Year: 2013 Page: 408-412
Author(s): Luiz R. G. Filho,Gustavo Y. Miyake,Carlos H. T. P. da Silva

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