Search Result "PIM profile."


The Pim Kinases: New Targets for Drug Development

Journal: Current Drug Targets
Volume: 12 Issue: 1 Year: 2011 Page: 2059-2066
Author(s): Ronan Swords, Kevin Kelly, Jennifer Carew, Stefan Nawrocki, Devalingam Mahalingam, John Sarantopoulos, David Bearss, Francis Giles

Review Article

Potential Pharmacological Inhibitors of Pim Kinase Under Clinical Trials

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 8 Year: 2018 Page: 1100-1114
Author(s): Gomathi P. Jeyapal,Moola J.N. Chandrasekar,Rajendiran Krishnasamy,Jubie Selvaraj,Manal Mohammad,Moola J. Nanjan

Fighting Tumor Cell Survival: Advances in the Design and Evaluation of Pim Inhibitors

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 4114-4133
Author(s): F. Anizon, A. A. Shtil, V. N. Danilenko, P. Moreau

Research Article

Bioinformatics-Based Characterization of Proteins Related to SARS-CoV-2 Using the Polarity Index Method® (PIM®) and Intrinsic Disorder Predisposition

Journal: Current Proteomics
Volume: 19 Issue: 1 Year: 2022 Page: 51-64
Author(s): Carlos Polanco,Vladimir N. Uversky,Guy W. Dayhoff,Alberto Huberman,Thomas Buhse,Manlio F. Márquez,Gilberto Vargas-Alarcón,Jorge Alberto Castañón-González,Leire Andrés,Juan Luciano Dı́az-González,Karina González-Bañales

Density Functional Theory, Docking, Bioisosteric Replacement, Pharmacophore Perception, Physical Chemical Analyses of the Interactions of Novel PIM-1 Inhibitors with Suitable Pharmacokinetic Properties for Cancer Treatment

Journal: Current Physical Chemistry
Volume: 3 Issue: 4 Year: 2013 Page: 408-412
Author(s): Luiz R. G. Filho,Gustavo Y. Miyake,Carlos H. T. P. da Silva

Research Article

New Mechanistic Insight on the PIM-1 Kinase Inhibitor AZD1208 Using Multidrug Resistant Human Erythroleukemia Cell Lines and Molecular Docking Simulations

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 11 Year: 2019 Page: 914-926
Author(s): Maiara Bernardes Marques,Michael González-Durruthy,Bruna Félix da Silva Nornberg,Bruno Rodrigues Oliveira,Daniela Volcan Almeida,Ana Paula de Souza Votto,Luis Fernando Marins

Research Article

Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim-1 Kinase Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 12 Year: 2018 Page: 1711-1728
Author(s): Mahmoud A. Abdelaziz Mahmoud,Rafat M. Mohareb,Meshari. A. Al-Sharif

Research Article

Dengue Fever Virus Envelope Glycoproteins Variability CharacterizedBioinformatically

Journal: Current Analytical Chemistry
Volume: 19 Issue: 9 Year: 2023 Page: 642-668
Author(s): Vladimir N. Uversky,Francisco J. Roldan Gomez

Research Article

Bioinformatics Insights on the Physicochemical Properties of SCN5AMutant Proteins Associated with the Brugada Syndrome

Journal: Current Medicinal Chemistry
Volume: 30 Issue: 15 Year: 2023 Page: 1776-1796
Author(s): Manlio F. Márquez,Vladimir N. Uversky,Enrique H. Lemus,Martha R. Castro

Review Article

Indole: A Privileged Heterocyclic Moiety in the Management of Cancer

Journal: Current Organic Chemistry
Volume: 25 Issue: 6 Year: 2021 Page: 724-736
Author(s): Reyaz Hassan Mir,Roohi Mohi-ud-din,Taha Umair Wani,Mohammad Ovais Dar,Abdul Jaleel Shah,Bashir Lone,Chawla Pooja,Mubashir Hussain Masoodi

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