Search Result "O6-Methylguanine-DNA methyltransferase (MGMT)"


Strategies to Improve the Killing of Tumors Using Temozolomide: Targeting the DNA Repair Protein MGMT

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 3886-3892
Author(s): G. Jiang, L. -T. Li, Y. Xin, L. Zhang, Y. -Q. Liu, J. -N. Zheng

Posttranslational Regulation of O6-Methylguanine-DNA Methyltransferase (MGMT) and New Opportunities for Treatment of Brain Cancers

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 16 Issue: 6 Year: 2016 Page: 455-464
Author(s): Kalkunte S. Srivenugopal, Amit Rawat, Suryakant K. Niture, Ameya Paranjpe, Chinavenmani Velu, Sanjay N. Venugopal, Hanumantha Rao Madala, Debasish Basak, Surendra R. Punganuru

Research Article

Effect of O6-Substituted Guanine Analogs on O6-methylguanine DNA-methyltransferase Expression and Glioblastoma Cells Viability

Journal: Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2017 Page: 28-39
Author(s): Patrick-Denis St-Coeur, Marc Cormier, Veronique C. LeBlanc, Pier Jr. Morin, Mohamed Touaibia

Role of Mismatch Repair and MGMT in Response to Anticancer Therapies

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 8 Issue: 4 Year: 2008 Page: 368-380
Author(s): Ida Casorelli, Maria Teresa Russo, Margherita Bignami

Review Article

Current Translational Insights into MGMT Methylation Regulating Temozolomide Sensitivity and Resistance in Glioblastoma Multiforme

Journal: Current Pharmacogenomics and Personalized Medicine
Volume: 17 Issue: 2 Year: 2020 Page: 76-93
Author(s): Ishmeet Gulati,Harsh Patel,Bala Prabhakar,Sujit Nair

Temozolomide: Mechanisms of Action, Repair and Resistance

Journal: Current Molecular Pharmacology
Volume: 5 Issue: 1 Year: 2012 Page: 102-114
Author(s): Jihong Zhang, Malcolm F.G. Stevens, Tracey D. Bradshaw

Research Article

MGMT Epigenetics: The Influence of Gene Body Methylation and Other Insights Derived from Integrated Methylomic, Transcriptomic, and Chromatin Analyses in Various Cancer Types

Journal: Current Cancer Drug Targets
Volume: 21 Issue: 4 Year: 2021 Page: 360-374
Author(s): Manny D. Bacolod,Francis Barany

An Innovative Fluorescent Semi-quantitative Methylation-specific PCR Method for the Determination of MGMT Promoter Methylation is Reflecting Intra-tumor Heterogeneity

Journal: Current Cancer Drug Targets
Volume: 15 Issue: 7 Year: 2015 Page: 624-640
Author(s): Aurelia Nguyen,Michele Legrain,Georges Noel,Andres Coca,Nicolos Meyer(EA),Roland Schott,Christelle Lasthaus,Marie Pierrette Chenard,Marie Pierre Gaub,Jean Marc Lessinger,Dominique Guenot,Natacha Entz-Werle

Research Article

O-6-methylguanine-DNA Methyltransferase Inhibits Gastric Carcinoma Cell Migration and Invasion by Downregulation of Matrix Metalloproteinase 2

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 16 Issue: 9 Year: 2016 Page: 1125-1132
Author(s): Chenglong Li,Li Deng,Hugang Shen,Qingyou Meng,Aimin Qian,Hongfei Sang,Jiazeng Xia,Xiaoqiang Li

Cytosine Methyltransferases as Tumor Markers

Journal: Current Genomics
Volume: 11 Issue: 8 Year: 2010 Page: 568-577
Author(s): Athanasia Pavlopoulou, Sophia Kossida

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