Search Result "Inhibit VEGFR-2 Activity"


Research Article

Molecular Design and Synthesis of New 3,4-Dihydropyrimidin-2(1H)-Ones as Potential Anticancer Agents with VEGFR-2 Inhibiting Activity

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 19 Issue: 3 Year: 2019 Page: 310-322
Author(s): Amany S. Mostafa,Waleed A. Bayoumi,Mohamed El-Mesery,Abdelaziz Elgaml

Pharmacophore Generation and 3D-QSAR of Novel 2-(quinazolin-4- ylamino)-[1,4] Benzoquinone Derivatives as VEGFR-2 Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 9 Issue: 10 Year: 2012 Page: 899-914
Author(s): Mahesh Kumar Teli,Pradeep Hanumanthappa,Rajanikant G. Krishnamurthy

Mini-Review Article

Anti-angiogenic Agents: A Review on Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Inhibitors

Journal: Current Medicinal Chemistry
Volume: 28 Issue: 13 Year: 2021 Page: 2540-2564
Author(s): Kang Cheng,Chen-Fu Liu,Guo-Wu Rao

Research Article

Molecular Insight and Binding Pattern Analysis of Shikonin as a Potential VEGFR-2 Inhibitor

Journal: Current Enzyme Inhibition
Volume: 13 Issue: 3 Year: 2017 Page: 235-244
Author(s): Raju Dash,Md. Junaid,Nazrul Islam,Md. Forhad Chowdhury Akash,Md. Imran Khan,Md. Arifuzzaman,Mahmuda Khatun,S. M. Zahid Hosen

Synthesis and Evaluation of Vascular Endothelial Growth Factor Receptor-2 Inhibitory Activity of 6,7-Dimethoxycinnoline Derivatives

Journal: Letters in Drug Design & Discovery
Volume: 10 Issue: 10 Year: 2013 Page: 984-988
Author(s): Xingjun Yao,Hongfa Yang,Yanhui Wan,Li Bie,Xinrui Liu,Zhonghui Liu

Anti-Angiogenic Therapy: Strategies to Develop Potent VEGFR-2 Tyrosine Kinase Inhibitors and Future Prospect

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 10 Year: 2016 Page: 1000-1040
Author(s): Leilei Shi,Jianfeng Zhou,Jifeng Wu,Yuemao Shen,Xun Li

Research Article

Discovery of New Quinazoline Derivatives as VEGFR-2 Inhibitors: Design, Synthesis,and Anti-proliferative Studies

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 23 Issue: 18 Year: 2023 Page: 2042-2055
Author(s): Sachin A. Dhawale,Pratap S. Dabhade,Santosh N. Mokale

Research Article

Molecular Docking and In Vitro Anticancer Screening of Synthesized Arylthiazolelinked 2H-indol-2-one Derivatives as VEGFR-2 Kinase Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 22 Issue: 11 Year: 2022 Page: 2166-2180
Author(s): Nishtha Shalmali,Sandhya Bawa,Md Rahmat Ali,Sourav Kalra,Raj Kumar,Bushra Zeya,Moshahid Alam Rizvi,Sangh Partap,Asif Husain

Research Article

ZnO Nanoparticles Catalyst in the Synthesis of Bioactive Fused Pyrimidines as Anti-breast Cancer Agents Targeting VEGFR-2

Journal: Medicinal Chemistry
Volume: 15 Issue: 3 Year: 2019 Page: 277-286
Author(s): Dina H. Dawood,Eman M. H. Abbas,Thoraya A. Farghaly,Mamdouh M. Ali,Mohammed F. Ibrahim

Research Article

New Thieno[2,3-d]pyrimidines as Anticancer VEGFR-2 Inhibitors with Apoptosis Induction: Design, Synthesis, and Biological and In Silico Studies

Journal: Medicinal Chemistry
Volume: 20 Issue: 9 Year: 2024 Page: 876-899
Author(s): Eman A. Sobh,Mohammed A. Dahab,Eslam B. Elkaeed,Bshra A. Alsfouk,Ibrahim M. Ibrahim,Ahmed M. Metwaly,Ibrahim H. Eissa

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