Search Result "Gamma Secretase"


In Silico Screening of Drugs to Find Potential Gamma-Secretase Inhibitors Using Pharmacophore Modeling, QSAR and Molecular Docking Studies

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 9 Year: 2014 Page: 770-780
Author(s): Arun Ekiri Vaidyanathan Raman,Karthic Krishnan,Arun Maurya,Nandini Sarkar

Research Article

Identification of High-affinity Small Molecules Targeting Gamma Secretase for the Treatment of Alzheimer’s Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 13 Year: 2019 Page: 1173-1187
Author(s): Meer Asif Ali,Sugunakar Vuree,Himshikha Goud,Tajamul Hussain,Anuraj Nayarisseri,Sanjeev Kumar Singh

Review of Synthesis, Assay, and Prediction of β and γ-secretase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 8 Year: 2012 Page: 828-844
Author(s): Helena Nino,Jose Enrique Rodriguez-Borges,Xerardo Garcia-Mera,Francisco Prado-Prado

Gamma-Secretase as a Pharmacological Target in Alzheimer Disease Research: When, Why and How?

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 3 Year: 2006 Page: 4313-4335
Author(s): Chewki Ziani-Cherif, Bachir Mostefa-Kara, Fatima Z. Brixi-Gormat

Computer-Aided Drug Design Applied to Beta and Gamma Secretase Inhibitors-Perspectives for New Alzheimer Disease Therapy

Journal: Current Enzyme Inhibition
Volume: 2 Issue: 4 Year: 2006 Page: 311-328
Author(s): Speranta Avram, Adina L. Milac, Dan F. Mihailescu, Aurelia Dabu, Maria L. Flonta

The Search for γ-Secretase and Development of Inhibitors

Journal: Current Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2002 Page: 1087-1106
Author(s): Jui-Yi Tsai, Michael S. Wolfe, Weiming Xia

Review Article

Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia

Journal: Current Drug Targets
Volume: 22 Issue: 15 Year: 2021 Page: 1789-1798
Author(s): Bhupendra Kaushik,Dilipkumar Pal,Supriyo Saha

Review Article

Gamma Secretase as an Important Drug Target for Management ofAlzheimer’s Disease: A Comprehensive Review

Journal: Current Topics in Medicinal Chemistry
Volume: 24 Issue: 2 Year: 2024 Page: 109-127
Author(s):

γ-Secretase Modulators

Journal: Current Alzheimer Research
Volume: 4 Issue: 5 Year: 2007 Page: 571-573
Author(s): Michael S. Wolfe

Presenilin and γ -Secretase Activity: A Viable Therapeutic Target for Alzheimers Disease?

Journal: Current Signal Transduction Therapy
Volume: 5 Issue: 2 Year: 2010 Page: 128-140
Author(s): Run Yan, Justin V. McCarthy

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