Search Result "DFG-loop"


Rational Approaches Towards Lead Optimization of Kinase Inhibitors: The Issue of Specificity

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 26 Year: 2013 Page: 4714-4738
Author(s): Preethi Badrinarayan,G. Narahari Sastry

Recent Advances in Small Molecule Inhibitors of VEGFR and EGFR Signaling Pathways

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1571-1590
Author(s): Haizhen Zhong, J. Phillip Bowen

Discovery of Small Molecule c-Met Inhibitors: Evolution and Profiles of Clinical Candidates

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 7-27
Author(s): Ted L. Underiner, Torsten Herbertz, Sheila J. Miknyoczki

Letter Article

Conformational Dynamics Analysis of MEK1 Using Hydrogen/Deuterium Exchange Mass Spectrometry

Journal: Protein & Peptide Letters
Volume: 28 Issue: 5 Year: 2021 Page: 481-488
Author(s): Min Woo Yun,Kiae Kim,Ji Young Park,Ka Young Chung

New Insights in Protein Kinase Conformational Dynamics

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 17 Year: 2012 Page: 1889-1895
Author(s): Giorgio Saladino,Francesco Luigi Gervasio

Targeting Protein Multiple Conformations: A Structure-Based Strategy for Kinase Drug Design

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1394-1407
Author(s): Liao Jie-Lou Jeffrey, Andrews C. Robert

The Use of Structural Biology in Janus Kinase Targeted Drug Discovery

Journal: Current Drug Targets
Volume: 12 Issue: 4 Year: 2011 Page: 546-555
Author(s): Nilda L. Alicea-Velazquez, Titus J. Boggon

Review Article

Rational Drug Design Approach of Receptor Tyrosine Kinase Type III Inhibitors

Journal: Current Medicinal Chemistry
Volume: 26 Issue: 42 Year: 2019 Page: 7623-7640
Author(s): Cheolhee Kim,Eunae Kim

Review Article

Chronic Myeloid Leukemia: Existing Therapeutic Options and Strategies to Overcome Drug Resistance

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 19 Issue: 4 Year: 2019 Page: 333-345
Author(s): Vivek Kumar Singh,Mohane Selvaraj Coumar

Research Article

Pharmacophore and Docking Guided Virtual Screening Study for Discovery of Type I Inhibitors of VEGFR-2 Kinase

Journal: Current Computer-Aided Drug Design
Volume: 13 Issue: 3 Year: 2017 Page: 186-207
Author(s): Heena R. Bhojwani,Urmila J. Joshi

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