Search Result "CDK2 inhibitors"


Review Article

Cyclin-Dependent Kinase-2 as a Target for Cancer Therapy: Progress in the Development of CDK2 Inhibitors as Anti-Cancer Agents

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 2 Year: 2015 Page: 237-263
Author(s): Tahir Ali Chohan, Haiyan Qian, Youlu Pan, Jian-Zhong Chen

An Analysis of the Binding Modes of ATP-Competitive CDK2 Inhibitors as Revealed by X-Ray Structures of Protein-Inhibitor Complexes

Journal: Current Medicinal Chemistry - Anti-Cancer Agents
Volume: 5 Issue: 5 Year: 2005 Page: 561-573
Author(s): A. Vulpetti, P. Pevarello

Chemical and Biological Profile of Dual Cdk1 and Cdk2 Inhibitors

Journal: Current Medicinal Chemistry - Anti-Cancer Agents
Volume: 3 Issue: 1 Year: 2003 Page: 1-14
Author(s): Stephan Ruetz, Doriano Fabbro, Juerg Zimmermann, Thomas Meyer, Nathanael Gray

3D-QSAR CoMFA Study on Oxindole Derivatives as Cyclin Dependent Kinase 1 (CDK1) and Cyclin Dependent Kinase 2 (CDK2) Inhibitors

Journal: Medicinal Chemistry
Volume: 3 Issue: 1 Year: 2007 Page: 75-84
Author(s): Sanjeev Kumar Singh, Nigus Dessalew, Prasad V. Bharatam

Research Article

Identification of Novel Cyclin A2 Binding Site and Nanomolar Inhibitors of Cyclin A2-CDK2 Complex

Journal: Current Computer-Aided Drug Design
Volume: 17 Issue: 1 Year: 2021 Page: 57-68
Author(s): Stephanie S. Kim,Michele J. Alves,Patrick Gygli,Jose Otero,Steffen Lindert

X-Ray Crystallographic Studies of CDK2, a Basis for Cyclin-Dependent Kinase Inhibitor Design in Anti-Cancer Drug Research

Journal: Current Medicinal Chemistry - Anti-Cancer Agents
Volume: 3 Issue: 1 Year: 2003 Page: 15-23
Author(s): Pascal Furet

Research Article

Evaluation of Benzamide-Chalcone Derivatives as EGFR/CDK2 Inhibitor: Synthesis,In-Vitro Inhibition, and Molecular Modeling Studies

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 22 Issue: 2 Year: 2022 Page: 328-343
Author(s): Akshada Joshi,Heena Bhojwani,Ojas Wagal,Khushboo Begwani,Urmila Joshi,Sadhana Sathaye,Divya Kanchan

Exploring QSAR on 4-Cyclohexylmethoxypyrimidines as Antitumor Agents for Their Inhibitory Activity of CDK2

Journal: Letters in Drug Design & Discovery
Volume: 7 Issue: 9 Year: 2010 Page: 625-631
Author(s): A. Ece, F. Sevin

Solution Phase Synthesis of a 3,5,7-Substituted Indolin-2-one Library as Potential CDK2 Inhibitor Isosteres

Journal: Letters in Drug Design & Discovery
Volume: 5 Issue: 1 Year: 2008 Page: 43-47
Author(s): Dmytro O. Tymoshenko, Brian T. Gregg, Matthew J. Hirsch, Jennifer L. Butcher

Perspective

Clinical CDK2 Inhibitors: Trends to Selectivity and Efficacy

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 18 Issue: 2 Year: 2023 Page: 102-107
Author(s): Polina V. Rusina,Alexey A. Lisov,Alexandra A. Denisova,Erik R. Gandalipov,Fedor N. Novikov,Alexander A. Shtil

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