Search Result "β-secretase (BACE1)"


Research Article

Berberine Alleviates Amyloid-Beta Pathology in the Brain of APP/PS1 Transgenic Mice via Inhibiting β/γ-Secretases Activity and Enhancing α-Secretases

Journal: Current Alzheimer Research
Volume: 15 Issue: 11 Year: 2018 Page: 1045-1052
Author(s): Zhiyou Cai,Chuanling Wang,Wenbo He,Yi Chen

Review Article

Is It the Twilight of BACE1 Inhibitors?

Journal: Current Neuropharmacology
Volume: 19 Issue: 1 Year: 2021 Page: 61-77
Author(s): Martina Hrabinova,Jaroslav Pejchal,Tomas Kucera,Daniel Jun,Monika Schmidt,Ondrej Soukup

BACE1 Inhibitors: Attractive Therapeutics for Alzheimer’s Disease

Ebook: Drug Design and Discovery in Alzheimer's Disease
Volume: 1 Year: 2015
Author(s): Boris Decourt,MiMi Macias,Marwan Sabbagh,Abdu Adem
Doi: 10.1016/B978-0-12-803959-5.50010-6

Review Article

The β-Secretase Enzyme BACE1: A Biochemical Enigma for Alzheimer’s Disease

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 19 Issue: 3 Year: 2020 Page: 184-194
Author(s): Hirak Shah,Ashish Patel,Vruti Parikh,Afzal Nagani,Bhargav Bhimani,Umang Shah,Tushar Bambharoliya

BACE1 Structure and Function in Health and Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 100-120
Author(s): Sarah L. Cole, Roger Vassar

Review Article

Current Updates on the Regulation of Beta-Secretase Movement as a Potential Restorative Focus for Management of Alzheimer's Disease

Journal: Protein & Peptide Letters
Volume: 26 Issue: 8 Year: 2019 Page: 579-587
Author(s): Syed Sayeed Ahmad,Mohammad Amjad Kamal

Research Article

Serum Starvation Induces BACE1 Processing and Secretion

Journal: Current Alzheimer Research
Volume: 14 Issue: 4 Year: 2017 Page: 453-459
Author(s): A. V. Stavropoulou,O. Mavrofrydi,P. Saftig,S. Efthimiopoulos

The Basic Biology of BACE1: A Key Therapeutic Target for Alzheimers Disease

Journal: Current Genomics
Volume: 8 Issue: 8 Year: 2007 Page: 509-530
Author(s): R. Vassar, S. L. Cole

BACE1 Dependent Neuregulin Processing: Review

Journal: Current Alzheimer Research
Volume: 9 Issue: 2 Year: 2012 Page: 178-183
Author(s): Daniel Fleck, Alistair N. Garratt, Christian Haass, Michael Willem

Fragment-based Designing for the Generation of Novel Leads Against BACE1

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2015 Page: 52-64
Author(s): Sucharita Das,Sandipan Chakraborty,Soumalee Basu

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