Search Result "γ-secretase modulation,"


In Silico Screening of Drugs to Find Potential Gamma-Secretase Inhibitors Using Pharmacophore Modeling, QSAR and Molecular Docking Studies

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 9 Year: 2014 Page: 770-780
Author(s): Arun Ekiri Vaidyanathan Raman,Karthic Krishnan,Arun Maurya,Nandini Sarkar

Research Article

Identification of High-affinity Small Molecules Targeting Gamma Secretase for the Treatment of Alzheimer’s Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 13 Year: 2019 Page: 1173-1187
Author(s): Meer Asif Ali,Sugunakar Vuree,Himshikha Goud,Tajamul Hussain,Anuraj Nayarisseri,Sanjeev Kumar Singh

Review Article

Gamma Secretase as an Important Drug Target for Management ofAlzheimer’s Disease: A Comprehensive Review

Journal: Current Topics in Medicinal Chemistry
Volume: 24 Issue: 2 Year: 2024 Page: 109-127
Author(s):

Review Article

Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia

Journal: Current Drug Targets
Volume: 22 Issue: 15 Year: 2021 Page: 1789-1798
Author(s): Bhupendra Kaushik,Dilipkumar Pal,Supriyo Saha

Gamma-Secretase as a Pharmacological Target in Alzheimer Disease Research: When, Why and How?

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 3 Year: 2006 Page: 4313-4335
Author(s): Chewki Ziani-Cherif, Bachir Mostefa-Kara, Fatima Z. Brixi-Gormat

γ-Secretase Modulators

Journal: Current Alzheimer Research
Volume: 4 Issue: 5 Year: 2007 Page: 571-573
Author(s): Michael S. Wolfe

γ-Secretase Inhibition and Modulation for Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 158-164
Author(s): Michael S. Wolfe

Role of the APP Non-Amyloidogenic Signaling Pathway and Targeting α-Secretase as an Alternative Drug Target for Treatment of Alzheimers Disease

Journal: Current Medicinal Chemistry
Volume: 14 Issue: 2 Year: 2007 Page: 2848-2864
Author(s): S. Bandyopadhyay, L. E. Goldstein, D. K. Lahiri, J. T. Rogers

From the Multifactorial Nature of Alzheimer`s Disease to Multitarget Therapy: The Contribution of the Translational Approach

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 1843-1852
Author(s):

Characterization of the Effect of a Novel γ-secretase Modulator on Aβ: A Clinically Translatable Model

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 1 Year: 2014 Page: 2484-2490
Author(s): Erik Portelius, Paulina Appelkvist, Kia Stromberg, Kina Hoglund

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