Search Result "γ-secretase"


In Silico Screening of Drugs to Find Potential Gamma-Secretase Inhibitors Using Pharmacophore Modeling, QSAR and Molecular Docking Studies

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 9 Year: 2014 Page: 770-780
Author(s): Arun Ekiri Vaidyanathan Raman,Karthic Krishnan,Arun Maurya,Nandini Sarkar

Research Article

Identification of High-affinity Small Molecules Targeting Gamma Secretase for the Treatment of Alzheimer’s Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 13 Year: 2019 Page: 1173-1187
Author(s): Meer Asif Ali,Sugunakar Vuree,Himshikha Goud,Tajamul Hussain,Anuraj Nayarisseri,Sanjeev Kumar Singh

Computer-Aided Drug Design Applied to Beta and Gamma Secretase Inhibitors-Perspectives for New Alzheimer Disease Therapy

Journal: Current Enzyme Inhibition
Volume: 2 Issue: 4 Year: 2006 Page: 311-328
Author(s): Speranta Avram, Adina L. Milac, Dan F. Mihailescu, Aurelia Dabu, Maria L. Flonta

Review of Synthesis, Assay, and Prediction of β and γ-secretase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 8 Year: 2012 Page: 828-844
Author(s): Helena Nino,Jose Enrique Rodriguez-Borges,Xerardo Garcia-Mera,Francisco Prado-Prado

Review Article

Gamma Secretase as an Important Drug Target for Management ofAlzheimer’s Disease: A Comprehensive Review

Journal: Current Topics in Medicinal Chemistry
Volume: 24 Issue: 2 Year: 2024 Page: 109-127
Author(s):

Review Article

Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia

Journal: Current Drug Targets
Volume: 22 Issue: 15 Year: 2021 Page: 1789-1798
Author(s): Bhupendra Kaushik,Dilipkumar Pal,Supriyo Saha

Gamma-Secretase as a Pharmacological Target in Alzheimer Disease Research: When, Why and How?

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 3 Year: 2006 Page: 4313-4335
Author(s): Chewki Ziani-Cherif, Bachir Mostefa-Kara, Fatima Z. Brixi-Gormat

In Vitro and In Vivo Metabolism of a Gamma-Secretase Inhibitor BMS-299897 and Generation of Active Metabolites in Milligram Quantities with a Microbial Bioreactor

Journal: Current Drug Metabolism
Volume: 7 Issue: 8 Year: 2006 Page: 883-896
Author(s): Donglu Zhang, Ronald Hanson, Vikram Roongta, Douglas D. Dischino, Qi Gao, Charles P. Sloan, Craig Polson, Daniel Keavy, Ming Zheng, James Mitroka, Suzanne Wehrli, Suresh Yeola

Review Article

Insight γ-Secretase: Structure, Function, and Role in Alzheimer’s Disease

Journal: Current Drug Targets
Volume: 22 Issue: 12 Year: 2021 Page: 1376-1403
Author(s): Suvadeep Mal,Udita Malik,Dilipkumar Pal,Abhishek Mishra

From the Multifactorial Nature of Alzheimer`s Disease to Multitarget Therapy: The Contribution of the Translational Approach

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 1843-1852
Author(s):

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