Properties and Clinical Development of a Novel Coating Technology: The poly[bis(trifluoroethoxy)phosphazene]

Title: Properties and Clinical Development of a Novel Coating Technology: The poly[bis(trifluoroethoxy)phosphazene]

Volume: 4 Issue: 1

Author(s): Davide Capodanno and Corrado Tamburino

Affiliation:

Keywords: Polymer, coating, stent

Abstract: Ultrapure poly[bis(trifluoroethoxy)phosphazene] is a novel biocompatible, anti-inflammatory, antithrombogenic polymer which has the potential to cover stent devices without elution of a cell cycle inhibiting drug. The properties of polyphosphazene are likely to extend its use to a broad array of promising applications. This article reviews the features of the polymer and some recent patents related to use of poly[bis(trifluoroethoxy)phosphazene] in coating, its relevance as compared to other polymers, current evidence on pre-clinical and clinical performance, and future perspectives.

Cite this article as:

Capodanno Davide and Tamburino Corrado, Properties and Clinical Development of a Novel Coating Technology: The poly[bis(trifluoroethoxy)phosphazene], Recent Patents on Drug Delivery & Formulation 2010; 4 (1) . https://dx.doi.org/10.2174/187221110789957264