Fabrication and Physicochemical and Medicinal Characterization of Nano Traditional Chinese Medicine

Ma      Peiyan; Fu      Zhengyi; Su      Yanli; Wang      Weimin; Wang      Hao; Zhang      Jinyong; Wang      Yucheng; Zhang      Qingjie

doi:10.2174/187221208784705288

Abstract

This paper discusses the present status of, and future perspectives on nano Traditional Chinese medicine (TCM) by describing the concept, its methodologies, preservation, drug effect and pharmacological study. The explanation and discussion are made from the recent study of nano TCM. Several types of nano Traditional Chinese medicine are prepared by High speed centrifugal sheering pulverizer (HSCS pulverizer) and the physicochemical characterization of nano particles is discussed. The typical serumal experiments are completed to prove the remarkable medicinal effect of nano TCM particles. When the medicine is pulverized to nano particles, the natural barrier of cell membrane and cell wall are broken into pieces. The medicine can be extracted faster and more adequately. Conclusions are drawn that the medicinal effects of nano particles can be improved. So the Nano TCM will have a profound effect on the Chinese drugs pharmaceutics. More experimental data should be studied in order to evaluate the medicinal effects of nano TCM further.

Keywords: Nano particles, Traditional Chinese Medicine, fabrication, methodologies, preservation, drug effect, pharmacological study, Radix salvia miltiorrhiza, Liuwei Dihuang, Ganoderma lucidum spores