Near-Infrared Dyes: Probe Development and Applications in Optical Molecular Imaging

Title: Near-Infrared Dyes: Probe Development and Applications in Optical Molecular Imaging

Volume: 8 Issue: 4

Author(s): Donald D. Nolting, John C. Gore and Wellington Pham

Affiliation:

Keywords: Cyanine, fluorescence, FRET, imaging, optical, probe, rhodamine, near-infrared (NIR) region, near-infrared (NIR) dyes, Fluorescent Dyes, Cyanine Dyes

Abstract: The recent emergence of optical imaging has brought forth a unique challenge for chemists: development of new biocompatible dyes that fluoresce in the near-infrared (NIR) region for optimal use in biomedical applications. This review describes the synthesis of NIR dyes and the design of probes capable of noninvasively imaging molecular events in small animal models.

Cite this article as:

D. Nolting Donald, C. Gore John and Pham Wellington, Near-Infrared Dyes: Probe Development and Applications in Optical Molecular Imaging, Current Organic Synthesis 2011; 8 (4) . https://dx.doi.org/10.2174/157017911796117223