Abstract
Asthma is amongst the commonest chronic illnesses of childhood yet there is no single objective test that results in a definitive diagnosis. Diagnosis remains clinical, especially in young children. At present, asthma diagnosis in children is best viewed as a process. The initial steps include a clinical assessment focusing on recognising characteristic clinical features from a detailed history and examination combined with a careful review of possible alternative diagnoses. Since there is no gold standard for diagnosis, clinical evaluation can only give a probability that a given child has a diagnosis of asthma. If the probability of asthma is high, the next step is frequently a trial of anti-asthma treatment, usually a low-dose of an inhaled corticosteroid and a bronchodilator. Fairly to respond to a properly taken anti-asthma treatment suggests an alternative diagnosis. If the probability is low, a diagnosis other than asthma may be suspected. Then further investigation and specialist referral may be indicated. In those with an intermediate probability tests of lung function (expiratory airway obstruction, bronchial reversibility and occasionally bronchial hyperreactivity), and tests for atopy may be helpful.
Current Pediatric Reviews
Title: Asthma in Childhood – Making the Diagnosis
Volume: 6 Issue: 2
Author(s): James Y. Paton
Affiliation:
Keywords: Children, asthma, diagnosis
Abstract: Asthma is amongst the commonest chronic illnesses of childhood yet there is no single objective test that results in a definitive diagnosis. Diagnosis remains clinical, especially in young children. At present, asthma diagnosis in children is best viewed as a process. The initial steps include a clinical assessment focusing on recognising characteristic clinical features from a detailed history and examination combined with a careful review of possible alternative diagnoses. Since there is no gold standard for diagnosis, clinical evaluation can only give a probability that a given child has a diagnosis of asthma. If the probability of asthma is high, the next step is frequently a trial of anti-asthma treatment, usually a low-dose of an inhaled corticosteroid and a bronchodilator. Fairly to respond to a properly taken anti-asthma treatment suggests an alternative diagnosis. If the probability is low, a diagnosis other than asthma may be suspected. Then further investigation and specialist referral may be indicated. In those with an intermediate probability tests of lung function (expiratory airway obstruction, bronchial reversibility and occasionally bronchial hyperreactivity), and tests for atopy may be helpful.
Export Options
About this article
Cite this article as:
Y. Paton James, Asthma in Childhood – Making the Diagnosis, Current Pediatric Reviews 2010; 6 (2) . https://dx.doi.org/10.2174/157339610791561132
DOI https://dx.doi.org/10.2174/157339610791561132 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Serendipity of Erythromycin in the Management of Periprosthetic Inflammation
Current Drug Therapy Use of Mouse Models to Evaluate Roles of Nuclear Receptors and their Ligands in the Pathogenesis and Treatment of Atherosclerosis
Current Drug Targets Near-infrared Light Responsive Upconversion Nanoparticles for Imaging, Drug Delivery and Therapy of Cancers
Current Nanoscience Naturally-occurring Dimers of Flavonoids as Anticarcinogens
Anti-Cancer Agents in Medicinal Chemistry Dynamic Contrast-Enhanced MRI in Oncology Drug Development
Current Clinical Pharmacology Neurotuberculosis: An Overview
Central Nervous System Agents in Medicinal Chemistry Immunotherapy in Allergies: An Update
Inflammation & Allergy - Drug Targets (Discontinued) Cytotoxic and Anticancer Activities of Isatin and Its Derivatives: A Comprehensive Review from 2000-2008
Anti-Cancer Agents in Medicinal Chemistry Allergic Contact Dermatitis: Novel Mechanisms and Therapeutic Perspectives
Current Drug Metabolism Oxidative Biotransformation of Fatty Acids by Cytochromes P450: Predicted Key Structural Elements Orchestrating Substrate Specificity, Regioselectivity and Catalytic Efficiency
Current Drug Metabolism EMT Blockage Strategies: Targeting Akt Dependent Mechanisms for Breast Cancer Metastatic Behaviour Modulation
Current Gene Therapy Macromolecular and Nanotechnological Modification of Camptothecin and its Analogs to Improve the Efficacy
Current Drug Discovery Technologies Exploring New CGRP Family Peptides and their Receptors in Vertebrates
Current Protein & Peptide Science Soy Phytoestrogens and Breast Cancer Chemoprevention: Molecular Mechanisms
Current Nutrition & Food Science Principles and Therapeutic Relevance for Targeting Mitochondria in Aging and Neurodegenerative Diseases
Current Pharmaceutical Design The Cone Beam O-Arm Imaging System: Radiation Dose, Image Quality, and Clinical Applications
Recent Patents on Medical Imaging Methylglyoxal, A Metabolite Increased in Diabetes is Associated with Insulin Resistance, Vascular Dysfunction and Neuropathies
Current Drug Metabolism Peptides as Therapeutic Agents or Drug Leads for Autoimmune, Hormone Dependent and Cardiovascular Diseases
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry The Pentacyclic Triterpenoids in Herbal Medicines and Their Pharmacological Activities in Diabetes and Diabetic Complications
Current Medicinal Chemistry Gut-liver Axis and Microbiota in NAFLD: Insight Pathophysiology for Novel Therapeutic Target
Current Pharmaceutical Design