Abstract
The endothelin (ET) axis plays a major role in cardiovascular diseases and a number of human cancers. This review summarizes the work that has been published in the past ten years using labeled endothelin receptor ligands for the visualization of endothelin receptor expression in vivo.
Keywords: Molecular imaging, endothelin axis, tumor angiogenesis, endothelial dysfunction, cardiovascular diseases
Mini-Reviews in Medicinal Chemistry
Title: Non-Invasive Approaches to Visualize the Endothelin Axis In Vivo Using State-of-the-Art Molecular Imaging Modalities
Volume: 9 Issue: 14
Author(s): C. Holtke, A. Faust, H-J. Breyholz, K. Kopka, O. Schober, B. Riemann, C. Bremer, M. Schafers and S. Wagner
Affiliation:
Keywords: Molecular imaging, endothelin axis, tumor angiogenesis, endothelial dysfunction, cardiovascular diseases
Abstract: The endothelin (ET) axis plays a major role in cardiovascular diseases and a number of human cancers. This review summarizes the work that has been published in the past ten years using labeled endothelin receptor ligands for the visualization of endothelin receptor expression in vivo.
Export Options
About this article
Cite this article as:
Holtke C., Faust A., Breyholz H-J., Kopka K., Schober O., Riemann B., Bremer C., Schafers M. and Wagner S., Non-Invasive Approaches to Visualize the Endothelin Axis In Vivo Using State-of-the-Art Molecular Imaging Modalities, Mini-Reviews in Medicinal Chemistry 2009; 9 (14) . https://dx.doi.org/10.2174/138955709791012210
DOI https://dx.doi.org/10.2174/138955709791012210 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Reactive Oxygen Production Induced by the Gut Microbiota: Pharmacotherapeutic Implications
Current Medicinal Chemistry General Aspects of Metal Toxicity
Current Medicinal Chemistry Gold Nanoparticles; Potential Nanotheranostic Agent in Breast Cancer: A Comprehensive Review with Systematic Search Strategy
Current Drug Metabolism 177Lu-DOTA-Bevacizumab: Radioimmunotherapy Agent for Melanoma
Current Radiopharmaceuticals Transferrin and the Transferrin Receptor: Of Magic Bullets and Other Concerns
Inflammation & Allergy - Drug Targets (Discontinued) A Review of Select Recent Patents on Novel Nanocarriers
Recent Patents on Drug Delivery & Formulation G Protein-Coupled Receptors and their Signaling Pathways: Classical Therapeutical Targets Susceptible to Novel Therapeutic Concepts
Current Pharmaceutical Design The Role of STAT3 Signaling in Different Types of Cancers: A Comprehensive Review
Current Enzyme Inhibition Transforming Growth Factor-β Signaling in Motor Neuron Diseases
Current Molecular Medicine Medical Data Assessment with Traditional, Machine-learning and Deeplearning Techniques
Current Medical Imaging Longevity Pathways: HSF1 and FoxO Pathways, a New Therapeutic Target to Prevent Age-Related Diseases
Current Aging Science A Cationic Liposomal Vincristine Formulation with Improved Vincristine Retention, Extended Circulation Lifetime and Increased Anti-Tumor Activity
Letters in Drug Design & Discovery Dysregulation of Lysyl Oxidases Expression in Diabetic Nephropathy and Renal Cell Carcinoma
Current Drug Targets Monitoring Molecular, Functional and Morphologic Aspects of Bone Metastases Using Non-Invasive Imaging
Current Pharmaceutical Biotechnology Mechanism of Oxidative Broncho-Epithelial Cell Damage with Reference to Gas Phase Cigarette Smoke
Mini-Reviews in Organic Chemistry Epigenetic Lesions in Malignant Melanoma
Current Pharmaceutical Biotechnology Patented Biomarker Panels in Early Detection of Cancer
Recent Patents on Biomarkers PAI-1 - A Potential Therapeutic Target in Cancer
Current Drug Targets A Systems Biology Road Map for the Discovery of Drugs Targeting Cancer Cell Metabolism
Current Pharmaceutical Design Improving DNA Vaccine Performance Through Vector Design
Current Gene Therapy