A New Approach to Tubacin

Title: A New Approach to Tubacin

Volume: 7 Issue: 1

Author(s): Jian Hong, Xin Xu, Debasis Das, Pengyu Yang, Shu-Hui Chen and Ge Li

Affiliation:

Keywords: Tubacin, histone deacetylases, allyl borane reaction, stereoselective ketal formation, solution phase synthesis, hydroxyamide synthesis

Abstract: A new simple synthesis of tubacin is reported. It entails the formation of the syn-1,3-diol unit and its stereoselective ketalization with a functionalized benzaldehyde derivative.

Cite this article as:

Hong Jian, Xu Xin, Das Debasis, Yang Pengyu, Chen Shu-Hui and Li Ge, A New Approach to Tubacin, Letters in Organic Chemistry 2010; 7 (1) . https://dx.doi.org/10.2174/157017810790533913