Abstract
Currently, statins are in lime light due to their pleiotropic effects. One of their pleiotropic effects is on glucose metabolism. Various clinical and preclinical studies were designed to evaluate statins effect on glucose metabolism. This review describes preclinical and clinical evidences of statins action on glucose metabolism.
Keywords: Statin, diabetes, insulin resistance, glucose metabolism, solubility
Mini-Reviews in Medicinal Chemistry
Title: Can Statin be a Novel Pharmacophore for Antidiabetic Activity?
Volume: 9 Issue: 12
Author(s): S. A. Parmar and A. A. Mehta
Affiliation:
Keywords: Statin, diabetes, insulin resistance, glucose metabolism, solubility
Abstract: Currently, statins are in lime light due to their pleiotropic effects. One of their pleiotropic effects is on glucose metabolism. Various clinical and preclinical studies were designed to evaluate statins effect on glucose metabolism. This review describes preclinical and clinical evidences of statins action on glucose metabolism.
Export Options
About this article
Cite this article as:
Parmar A. S. and Mehta A. A., Can Statin be a Novel Pharmacophore for Antidiabetic Activity?, Mini-Reviews in Medicinal Chemistry 2009; 9 (12) . https://dx.doi.org/10.2174/1389557789957340
DOI https://dx.doi.org/10.2174/1389557789957340 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
How Cardiomyocytes Make the Heart Old
Current Pharmaceutical Biotechnology Recent Drug Development Approaches in Thrombosis, Stroke and other Cardiovascular Diseases
Current Pharmaceutical Design Anti-TNF Treatment in Rheumatoid Arthritis
Current Pharmaceutical Design Clinical Applications of Positron Emission Tomography (PET) Imaging in Medicine: Oncology, Brain Diseases and Cardiology
Current Radiopharmaceuticals PDE5 Inhibitors in Non-Urological Conditions
Current Pharmaceutical Design Heart Failure in Minority Populations - Impediments to Optimal Treatment in Australian Aborigines
Current Cardiology Reviews Endothelial Dysfunction in Heart Failure: Mechanisms and Therapeutic Approaches
Current Vascular Pharmacology Stem Cells as In Vitro Models of Disease
Current Stem Cell Research & Therapy Rosuvastatin Ameliorates Obesity and Proteinuria in Zucker Diabetic Fatty Rats
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Complications of Diabetes: An Insight into Genetic Polymorphism and Role of Insulin
Recent Patents on Inflammation & Allergy Drug Discovery Cell Immunity in Coronary Artery Disease (CAD)
Current Immunology Reviews (Discontinued) <i>Panax notoginseng</i> Saponins Promote Cell Death and Chemosensitivity in Pancreatic Cancer through the Apoptosis and Autophagy Pathways
Anti-Cancer Agents in Medicinal Chemistry The Many Antithrombotic Actions of Nitric Oxide
Current Drug Targets Cardiac Sarcolemmal Ion Channels and Transporters as Possible Targets for Antiarrhythmic and Positive Inotropic Drugs: Strategies of the Past-Perspectives of the Future
Current Pharmaceutical Design The Melanocortin Receptor System: A Target for Multiple Degenerative Diseases
Current Protein & Peptide Science Patents on Metallic Biodegradable Stents
Recent Patents on Materials Science Ultra-micronized Palmitoylethanolamide: An Efficacious Adjuvant Therapy for Parkinson’s Disease
CNS & Neurological Disorders - Drug Targets Semicarbazide-Sensitive Amine Oxidase/Vascular Adhesion Protein 1: Recent Developments Concerning Substrates and Inhibitors of a Promising Therapeutic Target
Current Medicinal Chemistry Disease Modifying Osteoarthritis Drugs: Facing Development Challenges and Choosing Molecular Targets
Current Drug Targets microRNA in Chondrogenesis, Cartilage and Osteoarthritis
Current Rheumatology Reviews