The Fink Blueprint for Hsp70/Hsc70 Molecular Chaperones

Title: The Fink Blueprint for Hsp70/Hsc70 Molecular Chaperones

Volume: 10 Issue: 5

Author(s): Stephan N. Witt

Affiliation:

Keywords: Chaperone, heat shock protein, unfolded protein, ATPase

Abstract: In a Nature article published in 1993, Anthony L. Fink and colleagues reported how Hsp70 chaperones use ATP binding in the presence of K+, rather than hydrolysis, to accelerate substrate release. As of the summer of 2008, his article had received 297 citations. I discuss here the influence Tonys iconic article has had on the chaperone field.

Cite this article as:

Witt N. Stephan, The Fink Blueprint for Hsp70/Hsc70 Molecular Chaperones, Current Protein & Peptide Science 2009; 10 (5) . https://dx.doi.org/10.2174/138920309789352047

DOI https://dx.doi.org/10.2174/138920309789352047	Print ISSN 1389-2037
Publisher Name Bentham Science Publisher	Online ISSN 1875-5550