Generic placeholder image

Current Protein & Peptide Science

Editor-in-Chief

ISSN (Print): 1389-2037
ISSN (Online): 1875-5550

Crystallographic Cryoenzymology and the Legacy of Tony Fink

Author(s): Gregory A. Petsko

Volume 10, Issue 5, 2009

Page: [416 - 423] Pages: 8

DOI: 10.2174/138920309789351985

Price: $65

Abstract

During the past thirty years significant contributions to our understanding of the structural origins of the catalytic power of enzymes have come from solution and crystallographic studies of enzyme-substrate and enzymeintermediate complexes trapped at subzero temperatures, a field that was pioneered in large part by Anthony L. Fink and Pierre Douzou. Here I review, from a personal perspective, the history of crystallographic cryoenzymology, with an emphasis on the contributions of Tony Fink. The story has a moral: if you choose your collaborators based not only on their scientific prowess but also on their human qualities, the resulting friendships will enrich your life.


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy