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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Structural and Functional Diversity Among Eukaryotic Hsp70 Nucleotide Exchange Factors

Author(s): Mehdi Kabani

Volume 16, Issue 6, 2009

Page: [623 - 630] Pages: 8

DOI: 10.2174/092986609788490186

Price: $65

Abstract

Since their recent identification, eukaryotic Hsp70 nucleotide exchange factors (NEFs) have gained increasing interest due to their engagement in vital cellular processes. Here, I summarize our current knowledge of their mechanisms of action, regulations and cellular functions as well as their relevance for human diseases such as cystic fibrosis or amyloidoses.


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