Abstract
Only 5-15% of the ∼25000 existing species of plants have been examined for the presence of biologically active compounds. The ancient medical systems use a much larger palette of herbs for therapy. Systematic drug discovery involving using cues provided from traditional medical systems is bound to produce a new generation of green drugs. Curcumin the primary active ingredient in Curcuma longa is used as a model to enunciate the concept of green drug development. Synthetic and formulation based approaches to optimize the bioactivity of curcumin is presented.
Keywords: Green drug, curcumin, traditional medicine, GRAS, renewable resource, derivative
Mini-Reviews in Organic Chemistry
Title: The Concept of a Green Drug, Curcumin and It ’ s Derivatives as a Model System
Volume: 6 Issue: 2
Author(s): K. S. Raja, R. Balambika, S. Dolai and W. Shi
Affiliation:
Keywords: Green drug, curcumin, traditional medicine, GRAS, renewable resource, derivative
Abstract: Only 5-15% of the ∼25000 existing species of plants have been examined for the presence of biologically active compounds. The ancient medical systems use a much larger palette of herbs for therapy. Systematic drug discovery involving using cues provided from traditional medical systems is bound to produce a new generation of green drugs. Curcumin the primary active ingredient in Curcuma longa is used as a model to enunciate the concept of green drug development. Synthetic and formulation based approaches to optimize the bioactivity of curcumin is presented.
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Cite this article as:
Raja S. K., Balambika R., Dolai S. and Shi W., The Concept of a Green Drug, Curcumin and It ’ s Derivatives as a Model System, Mini-Reviews in Organic Chemistry 2009; 6 (2) . https://dx.doi.org/10.2174/157019309788167684
DOI https://dx.doi.org/10.2174/157019309788167684 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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