Neonatal Persistent Pulmonary Hypertension Associated with Congenital Cystic Adenomatoid Malformation Treated with Sildenafil: Case Report

Title: Neonatal Persistent Pulmonary Hypertension Associated with Congenital Cystic Adenomatoid Malformation Treated with Sildenafil: Case Report

Volume: 5 Issue: 2

Author(s): Gianfranco Maffei, Vincenzo Manuppelli and Rosario Magaldi

Affiliation:

Keywords: PPHN, CCAM, sildenafil, HFOV, oxygenation index

Abstract: We report a case with severe persistent pulmonary hypertension (PPHN) associated with congenital cystic adenomatoid malformation of the lung (CCAM) treated with sildenafil PO. The case was unresponsive to the High-Frequency Oscillatory Ventilation (HFOV), with a oxygenation index (OI) of 50 before sildenafil. Substantial improvement in OI was followed by extubation and survival. No side-effects were noted.

Cite this article as:

Maffei Gianfranco, Manuppelli Vincenzo and Magaldi Rosario, Neonatal Persistent Pulmonary Hypertension Associated with Congenital Cystic Adenomatoid Malformation Treated with Sildenafil: Case Report, Current Pediatric Reviews 2009; 5 (2) . https://dx.doi.org/10.2174/157339609788185767

DOI https://dx.doi.org/10.2174/157339609788185767	Print ISSN 1573-3963
Publisher Name Bentham Science Publisher	Online ISSN 1875-6336