Abstract
Investigations into the immunogenicity of the prion protein are ongoing. To combat its pathological isoform without affecting the cellular protein is a challenge in prion research. We here summarize the studies in which prion protein peptides have been used for immunization, to thus determine the most immunogenic parts of the prion protein.
Keywords: Prion protein, peptides, epitope prediction, immune response, vaccine
Mini-Reviews in Medicinal Chemistry
Title: Prion Protein Peptides as Vaccines
Volume: 9 Issue: 4
Author(s): M. Ghielmetti, T. Vranac and V. Curin Serbec
Affiliation:
Keywords: Prion protein, peptides, epitope prediction, immune response, vaccine
Abstract: Investigations into the immunogenicity of the prion protein are ongoing. To combat its pathological isoform without affecting the cellular protein is a challenge in prion research. We here summarize the studies in which prion protein peptides have been used for immunization, to thus determine the most immunogenic parts of the prion protein.
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Cite this article as:
Ghielmetti M., Vranac T. and Serbec Curin V., Prion Protein Peptides as Vaccines, Mini-Reviews in Medicinal Chemistry 2009; 9 (4) . https://dx.doi.org/10.2174/138955709787847903
DOI https://dx.doi.org/10.2174/138955709787847903 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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