Abstract
The linear naphtho-γ-pyrone (LNGP) moiety is a naturally occurring scaffold with broad biological activity ranging through antimicrobial, antiviral, insecticidal and anti-estrogenic activity. This review, the first of its kind, surveys the chemical literature in an effort directed toward assembling data that will facilitate the construction of activity profiles associated with this emerging class of compounds. The structural and associated biological information has been presented in tabular format with all structures revealed throughout the document and referencing that will allow the reader to rapidly access the literature pertaining to a specific activity or structural class.
Mini-Reviews in Medicinal Chemistry
Title: Linear Naphtho-γ-Pyrones: A Naturally Occurring Scaffold of Biological Importance
Volume: 9 Issue: 3
Author(s): R. A. Barrow and M. W.B. McCulloch
Affiliation:
Abstract: The linear naphtho-γ-pyrone (LNGP) moiety is a naturally occurring scaffold with broad biological activity ranging through antimicrobial, antiviral, insecticidal and anti-estrogenic activity. This review, the first of its kind, surveys the chemical literature in an effort directed toward assembling data that will facilitate the construction of activity profiles associated with this emerging class of compounds. The structural and associated biological information has been presented in tabular format with all structures revealed throughout the document and referencing that will allow the reader to rapidly access the literature pertaining to a specific activity or structural class.
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Cite this article as:
Barrow A. R. and McCulloch W.B. M., Linear Naphtho-γ-Pyrones: A Naturally Occurring Scaffold of Biological Importance, Mini-Reviews in Medicinal Chemistry 2009; 9 (3) . https://dx.doi.org/10.2174/1389557510909030273
DOI https://dx.doi.org/10.2174/1389557510909030273 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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