Abstract
Heat shock protein 90 has emerged as a promising target for the treatment of cancer and neurodegenerative diseases. This review summarizes recent advancements towards the development of natural products as they pertain to the biological and chemical understanding of this molecular chaperone.
Keywords: Hsp90, inhibitors, cancer, neurodegenerative diseases, natural products
Mini-Reviews in Medicinal Chemistry
Title: Natural Product Inhibitors of Hsp90: Potential Leads for Drug Discovery
Volume: 9 Issue: 2
Author(s): M. W. Amolins and B. S.J. Blagg
Affiliation:
Keywords: Hsp90, inhibitors, cancer, neurodegenerative diseases, natural products
Abstract: Heat shock protein 90 has emerged as a promising target for the treatment of cancer and neurodegenerative diseases. This review summarizes recent advancements towards the development of natural products as they pertain to the biological and chemical understanding of this molecular chaperone.
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Cite this article as:
Amolins W. M. and Blagg S.J. B., Natural Product Inhibitors of Hsp90: Potential Leads for Drug Discovery, Mini-Reviews in Medicinal Chemistry 2009; 9 (2) . https://dx.doi.org/10.2174/138955709787316056
DOI https://dx.doi.org/10.2174/138955709787316056 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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