Abstract
Recently, Canadian, US and European health regulatory agencies issued warnings about an increased risk of stroke and death in elderly patients with dementia receiving atypical antipsychotics. Assessing both randomised and nonrandomised evidence, this systematic review found conflicting findings, particularly for risperidone. More research is needed to better inform clinical practice.
Keywords: Neuroleptics, typical antipsychotics, atypical antipsychotics, dopamine, dementia, cerebrovascular events
Mini-Reviews in Medicinal Chemistry
Title: Antipsychotic Drugs and Cerebrovascular Events in Elderly Patients with Dementia: A Systematic Review
Volume: 8 Issue: 8
Author(s): Sara Mazzucco, Andrea Cipriani, Corrado Barbui and Salvatore Monaco
Affiliation:
Keywords: Neuroleptics, typical antipsychotics, atypical antipsychotics, dopamine, dementia, cerebrovascular events
Abstract: Recently, Canadian, US and European health regulatory agencies issued warnings about an increased risk of stroke and death in elderly patients with dementia receiving atypical antipsychotics. Assessing both randomised and nonrandomised evidence, this systematic review found conflicting findings, particularly for risperidone. More research is needed to better inform clinical practice.
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Cite this article as:
Mazzucco Sara, Cipriani Andrea, Barbui Corrado and Monaco Salvatore, Antipsychotic Drugs and Cerebrovascular Events in Elderly Patients with Dementia: A Systematic Review, Mini-Reviews in Medicinal Chemistry 2008; 8 (8) . https://dx.doi.org/10.2174/138955708784912175
DOI https://dx.doi.org/10.2174/138955708784912175 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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