HPLC as a Tool in Medicinal Chemistry for the Monitoring of Tricyclic Antidepressants in Biofluids

Title: HPLC as a Tool in Medicinal Chemistry for the Monitoring of Tricyclic Antidepressants in Biofluids

Volume: 8 Issue: 3

Author(s): V. F. Samanidou, M. K. Nika and I. N. Papadoyannis

Affiliation:

Keywords: HPLC, tricyclic antidepressants, monitoring, medicinal chemistry, biological fluids

Abstract: HPLC is discussed as an essential tool in medicinal chemistry for the monitoring of tricyclic antidepressants in biofluids, providing clinicians with efficient fast and reliable methods to define individual optimum therapeutic concentrations in treatment of depressions. Additional information on mechanism of action, structure activity relationship and metabolism is provided.

Cite this article as:

Samanidou F. V., Nika K. M. and Papadoyannis N. I., HPLC as a Tool in Medicinal Chemistry for the Monitoring of Tricyclic Antidepressants in Biofluids, Mini-Reviews in Medicinal Chemistry 2008; 8 (3) . https://dx.doi.org/10.2174/138955708783744038