Generic placeholder image

Infectious Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

Influenza Virus Hemagglutinin - Structural Studies and their Implications for the Development of Therapeutic Approaches

Author(s): James Stevens and Ruben O. Donis

Volume 7, Issue 4, 2007

Page: [329 - 335] Pages: 7

DOI: 10.2174/187152607783018727

Price: $65

Abstract

Possible adaptation of one of the currently circulating strains of highly pathogenic H5N1 avian influenza A virus to produce the next human influenza pandemic is an area of major global concern. Intense research is being focused on developing new generations of effective vaccines and antivirals. Here, we discuss the structure of hemagglutinin and its potential as a target for development of future therapeutics to mitigate the impact of any future influenza pandemic.

Keywords: Influenza, hemagglutinin, sialic acid, host restriction, pandemic, glycan microarray, antiviral, drug design


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy