Abstract
Endothelial dysfunction is thought to be an important factor in the development of atherosclerosis. Over the past decade, a non-invasive technique has evolved to evaluate flow-mediated vasodilation (FMD), an endothelium-dependent function, in the brachial artery. FMD decreases with increasing age and subjects with diabetes mellitus, hypercholesterolemia, smokers and hypertension have decreased FMD. There are a few concise studies reporting that FMD predicts cardiovascular events. However, the assumption that focal measurement of brachial artery FMD predicts coronary artery disease deserves further investigation.
Keywords: flow-mediated dilatation, brachial artery, cardiovascular risk factor?, flow-mediated vasodilation, hypercholesterolemia, coronary artery disease
Current Vascular Pharmacology
Title: Is Impaired Flow-Mediated Dilatation of the Brachial Artery a Cardiovascular Risk Factor?
Volume: 1 Issue: 2
Author(s): Stefan Agewall
Affiliation:
Keywords: flow-mediated dilatation, brachial artery, cardiovascular risk factor?, flow-mediated vasodilation, hypercholesterolemia, coronary artery disease
Abstract: Endothelial dysfunction is thought to be an important factor in the development of atherosclerosis. Over the past decade, a non-invasive technique has evolved to evaluate flow-mediated vasodilation (FMD), an endothelium-dependent function, in the brachial artery. FMD decreases with increasing age and subjects with diabetes mellitus, hypercholesterolemia, smokers and hypertension have decreased FMD. There are a few concise studies reporting that FMD predicts cardiovascular events. However, the assumption that focal measurement of brachial artery FMD predicts coronary artery disease deserves further investigation.
Export Options
About this article
Cite this article as:
Agewall Stefan, Is Impaired Flow-Mediated Dilatation of the Brachial Artery a Cardiovascular Risk Factor?, Current Vascular Pharmacology 2003; 1 (2) . https://dx.doi.org/10.2174/1570161033476745
DOI https://dx.doi.org/10.2174/1570161033476745 |
Print ISSN 1570-1611 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6212 |
Call for Papers in Thematic Issues
TREATMENT OF CARDIOVASCULAR DISEASE IN CHRONIC AND END STAGE KIDNEY DISEASE
Cardiovascular disease still remains the leading cause of death in Chronic and End Stage Kidney Disease, accounting for more than half of all deaths in dialysis patients. During the past decade, research has been focused on novel therapeutic agents that might delay or even reverse cardiovascular disease and vascular calcification, ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
QSAR Studies on some Calcium Channel Blockers
Letters in Drug Design & Discovery Soy Isoflavones and Cardiovascular Health: An Update
Current Nutrition & Food Science Heat Shock Proteins: Mediators of Atherosclerotic Development
Current Drug Targets Membrane Rafts in the Respiratory System
Current Respiratory Medicine Reviews Pharmacological Intervention in Type 2 Diabetes Mellitus – A Pathophysiologically Reasoned Approach?
Current Diabetes Reviews Designed Multiple Ligands: Basic Research vs Clinical Outcomes
Current Medicinal Chemistry Systemic Sclerosis-Related Interstitial Lung Disease
Current Respiratory Medicine Reviews Anti-Angiogenic Approaches to Malignant Gliomas
Current Cancer Drug Targets Nitric Oxide and Arginine Dysregulation: A Novel Pathway to Pulmonary Hypertension in Hemolytic Disorders
Current Molecular Medicine Mineralocorticoid Receptor Antagonism and Cardiac Remodeling in Ischemic Heart Failure
Current Medicinal Chemistry - Cardiovascular & Hematological Agents An Overview of the Pharmacogenetics and Molecular Genetics of ADHD
Current Pharmacogenomics Vascular Consequences of Aldosterone Excess and Mineralocorticoid Receptor Antagonism
Current Hypertension Reviews Withdrawal Notice: Atrial Fibrillation and Hypertension: “Quo Vadis”
Current Hypertension Reviews Impact of Diabetes on Vasculature: Focus on Nervous System
Current Diabetes Reviews Naringin Inhibits TNF-α Induced Oxidative Stress and Inflammatory Response in HUVECs via Nox4/NF-κ B and PI3K/Akt Pathways
Current Pharmaceutical Biotechnology DNA Damage and Epigenetic Changes in Kidney Diseases - Focused on Transcription Factors in Podocytes
Current Hypertension Reviews Cutaneous Complications of Anderson-Fabry Disease
Current Pharmaceutical Design The Role of Coronary Collaterals in Chronic Total Occlusions
Current Cardiology Reviews Initiation of the Immune Response by Extracellular Hsp72: Chaperokine Activity of Hsp72
Current Immunology Reviews (Discontinued) Acknowledgements to Reviewers
Current Hypertension Reviews