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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Inducible Nitric Oxide Synthase Inhibition by Mycophenolic Acid

Author(s): Dj. Miljkovic, M. Markovic and V. Trajkovic

Volume 4, Issue 7, 2004

Page: [741 - 746] Pages: 6

DOI: 10.2174/1389557043403585

Price: $65

Abstract

The focus of this review is the influence of an immunosuppressive xenobiotic drug mycophenolic acid on the induction of nitric oxide production in various cell types. The potential therapeutic significance of the cell-specific fine-tuning of nitric oxide release by mycophenolic acid, as well as the mechanisms behind the drug action are discussed.

Keywords: mycophenolic acid, mycophenolate mofetil, nitric oxide, inos


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