A2B Adenosine Receptor Antagonists: Recent Developments

Title: A2B Adenosine Receptor Antagonists: Recent Developments

Volume: 5 Issue: 12

Author(s): Barbara Cacciari, Giorgia Pastorin, Chiara Bolcato, Giampiero Spalluto, Magdalena Bacilieri and Stefano Moro

Affiliation:

Keywords: endogenous nucleoside, adenosine receptors subtypes, protein Kinase C (PKC), Xanthine Derivatives, Triazolo-Triazine Derivatives, GPCRs

Abstract: There are pharmacological evidences that A2B receptors are involved in inflammatory processes, such as asthma. For this reason, many efforts has been made for identifying selective A2B antagonists as antiasthmatic agents. The updated material related to this field has been rationalised and arranged in order to offer an overview of the topic.

Cite this article as:

Cacciari Barbara, Pastorin Giorgia, Bolcato Chiara, Spalluto Giampiero, Bacilieri Magdalena and Moro Stefano, A2B Adenosine Receptor Antagonists: Recent Developments, Mini-Reviews in Medicinal Chemistry 2005; 5 (12) . https://dx.doi.org/10.2174/138955705774933374