Abstract
BK polyoma virus-associated hemorrhagic cystitis has been described in patients who have had renal, bone marrow and cardiac transplantation. We report the first case of hemorrhagic cystitis associated with the BK virus in a 51 year old woman with scleroderma, who received bilateral lung transplantation. The pathological findings of the bladder were large cells with enlarged nuclei and scant cytoplasm (Decoy cells). The diagnosis was confirmed by immunohistochemical stains of the urinary bladder tissue and by blood and urine PCR. The patient required a cystectomy.
Keywords: BK polyoma virus, hemorrhagic cystitis, lung transplantation
Current Respiratory Medicine Reviews
Title: Severe Hemorrhagic Cystitis Associated with BK Polyoma Virus Infection Following Lung Transplantation
Volume: 1 Issue: 3
Author(s): Lingtak-Neander Chan, Malek G. Massad, Kamran Mahmood, Nina Clark, Sally Steinhiser, Jacques Kpodonu, Cimenga Tshibaka and Howard A. Jaffe
Affiliation:
Keywords: BK polyoma virus, hemorrhagic cystitis, lung transplantation
Abstract: BK polyoma virus-associated hemorrhagic cystitis has been described in patients who have had renal, bone marrow and cardiac transplantation. We report the first case of hemorrhagic cystitis associated with the BK virus in a 51 year old woman with scleroderma, who received bilateral lung transplantation. The pathological findings of the bladder were large cells with enlarged nuclei and scant cytoplasm (Decoy cells). The diagnosis was confirmed by immunohistochemical stains of the urinary bladder tissue and by blood and urine PCR. The patient required a cystectomy.
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Chan Lingtak-Neander, Massad G. Malek, Mahmood Kamran, Clark Nina, Steinhiser Sally, Kpodonu Jacques, Tshibaka Cimenga and Jaffe A. Howard, Severe Hemorrhagic Cystitis Associated with BK Polyoma Virus Infection Following Lung Transplantation, Current Respiratory Medicine Reviews 2005; 1 (3) . https://dx.doi.org/10.2174/157339805774598036
DOI https://dx.doi.org/10.2174/157339805774598036 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
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