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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

An Expeditious “Green” Michael Addition of Nitro Methane to Benzimidazole Chalcones in the Presence of TBAB as Surface Catalyst

Author(s): P.K. Dubey, P.V.V. Prasada Reddy and K. Srinivas

Volume 4, Issue 6, 2007

Page: [445 - 447] Pages: 3

DOI: 10.2174/157017807781467533

Price: $65

Abstract

A novel Michael addition of nitromethane to β-carbon of the benzimidazole chalcones 1 in the presence of K2CO3 and TBAB, under solvent-free conditions, by a simple physical mixing of compounds, leading to 1-(1-alkyl-1Hbenzimidazol- 2-yl)-4-nitro-3-aryl-butane-1-one 2 is described.

Keywords: Benzimidazole chalcones, nitromethane, K2CO3, TBAB, solvent-free, mortar and pestle


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