Abstract
Aptamers have been introduced to analytical applications, target validation, and drug discovery processes and, recently, applied directly as therapeutic agents. Aptamers can be generated by a method called SELEX (Systematic Evolution of Ligands by Exponential Enrichment). This is quite remarkable for such a young technology, which is only created in the early 1990s. This paper reviews recent new applications of aptamers in stem cell research and tissue engineering.
Keywords: Mesenchymal stem cells, aptamer, FACS analysis
Mini-Reviews in Medicinal Chemistry
Title: Aptamer-Based Strategies for Stem Cell Research
Volume: 7 Issue: 7
Author(s): Ke-Tai Guo, Richard Schafer, Angela Paul, Gerhard Ziemer, Hans P. Wendel, Ke-Tai Guo, Richard Schafer, Angela Paul, Gerhard Ziemer and Hans P. Wendel
Affiliation:
Keywords: Mesenchymal stem cells, aptamer, FACS analysis
Abstract: Aptamers have been introduced to analytical applications, target validation, and drug discovery processes and, recently, applied directly as therapeutic agents. Aptamers can be generated by a method called SELEX (Systematic Evolution of Ligands by Exponential Enrichment). This is quite remarkable for such a young technology, which is only created in the early 1990s. This paper reviews recent new applications of aptamers in stem cell research and tissue engineering.
Export Options
About this article
Cite this article as:
Ke-Tai Guo , Richard Schafer , Angela Paul , Gerhard Ziemer , Hans P. Wendel , Guo Ke-Tai, Schafer Richard, Paul Angela, Ziemer Gerhard and Wendel P. Hans, Aptamer-Based Strategies for Stem Cell Research, Mini-Reviews in Medicinal Chemistry 2007; 7 (7) . https://dx.doi.org/10.2174/138955707781024481
DOI https://dx.doi.org/10.2174/138955707781024481 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
A Link Between Chemical Structure and Biological Activity in Triterpenoids
Recent Patents on Anti-Cancer Drug Discovery Recurrent Left Atrial Low-grade Malignant Inflammatory Myofibroblastic Tumor Characterized by Cardiovascular Magnetic Resonance
Current Medical Imaging Cell Cycle and Cancer: The G1 Restriction Point and the G1 / S Transition
Current Genomics Breast Cancer Risks in Premenopausal Women: A Review
Current Women`s Health Reviews Titanocene Y - Transport and Targeting of an Anticancer Drug Candidate
Letters in Drug Design & Discovery Human 90 kDa Heat Shock Protein Hsp90 as a Target for Cancer Therapeutics
Current Chemical Biology The Targeted-liposome Delivery System of Antitumor Drugs
Current Drug Metabolism Combinatorial Carbohydrate Synthesis
Mini-Reviews in Organic Chemistry Preclinical and Clinical Studies of Chidamide (CS055/HBI-8000), An Orally Available Subtype-selective HDAC Inhibitor for Cancer Therapy
Anti-Cancer Agents in Medicinal Chemistry Synthesis and Evaluation of Cytotoxic Activity of Some Pyrroles and Fused Pyrroles
Anti-Cancer Agents in Medicinal Chemistry Targeting the Ubiquitin Proteasome System: Beyond Proteasome Inhibition
Current Pharmaceutical Design Clinical Development of MET Targeted Therapy For Human Cancer
Current Cancer Therapy Reviews Molecular Genetics and Targeted Therapy in Hepatocellular Carcinoma
Current Cancer Drug Targets The Endoplasmic Reticulum Alpha-Glycosidases as Potential Targets for Virus Control
Current Protein & Peptide Science Targeting Hsp90 in Non-Cancerous Maladies
Current Topics in Medicinal Chemistry Pharmacogenomics of Breast Cancer Targeted Therapy: Focus on Recent Patents
Recent Patents on DNA & Gene Sequences A Novel Hydroxysteroid-Sulfating Cytosolic Sulfotransferase, SULT3 ST3, from Zebrafish: Identification, Characterization, and Ontogenic Study
Drug Metabolism Letters Inhibition of HIV-1 Replication by RNA-Based Strategies
Current HIV Research Therapeutical Potential of CB<sub>2</sub> Receptors in Immune-Related Diseases
Current Molecular Pharmacology Pretreatment with Gallic Acid Mitigates Cyclophosphamide Induced Inflammation and Oxidative Stress in Mice
Current Molecular Pharmacology