Abstract
Artemisinin and its synthetic derivatives are widely used for antimalarial agents in the world. Moreover, they are discovered to additionally use as anticancer, antiangiogenesis, antiviral, immunosuppressive, and antifungal agents. Recent research results supported that it is a very promising field in drug discovery. In this review, it will discuss the structural and biological features of artemisinin and its derivatives that have published since 2003 except antimalarial, and show that they are useful lead compounds for novel drug discovery.
Keywords: Artemisinin, artemisinin derivatives, natural product, endoperoxide, lead compound, drug discovery
Mini-Reviews in Medicinal Chemistry
Title: Artemisinin, Promising Lead Natural Product for Various Drug Developments
Volume: 7 Issue: 4
Author(s): Seokjoon Lee
Affiliation:
Keywords: Artemisinin, artemisinin derivatives, natural product, endoperoxide, lead compound, drug discovery
Abstract: Artemisinin and its synthetic derivatives are widely used for antimalarial agents in the world. Moreover, they are discovered to additionally use as anticancer, antiangiogenesis, antiviral, immunosuppressive, and antifungal agents. Recent research results supported that it is a very promising field in drug discovery. In this review, it will discuss the structural and biological features of artemisinin and its derivatives that have published since 2003 except antimalarial, and show that they are useful lead compounds for novel drug discovery.
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Cite this article as:
Lee Seokjoon, Artemisinin, Promising Lead Natural Product for Various Drug Developments, Mini-Reviews in Medicinal Chemistry 2007; 7 (4) . https://dx.doi.org/10.2174/138955707780363837
DOI https://dx.doi.org/10.2174/138955707780363837 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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