Abstract
New prostaglandins analogues, containing heteroatoms in the cyclopentane ring were synthesized. The key step in the synthesis was the preparation of the five-membered ring starting from L-cysteine ethyl ester hydrochloride. The addition of the alkyl groups at C-15 position was also performed.
Keywords: Heterocyclic prostaglandins, azaprostaglandins, thiaprostaglandins
Letters in Organic Chemistry
Title: Synthesis of Novel Heterocyclic Prostaglandin Analogues
Volume: 4 Issue: 1
Author(s): Francisco C. Biaggio, Alessandra R. Rufino and Marcela C.F. Silveira
Affiliation:
Keywords: Heterocyclic prostaglandins, azaprostaglandins, thiaprostaglandins
Abstract: New prostaglandins analogues, containing heteroatoms in the cyclopentane ring were synthesized. The key step in the synthesis was the preparation of the five-membered ring starting from L-cysteine ethyl ester hydrochloride. The addition of the alkyl groups at C-15 position was also performed.
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Cite this article as:
Biaggio C. Francisco, Rufino R. Alessandra and Silveira C.F. Marcela, Synthesis of Novel Heterocyclic Prostaglandin Analogues, Letters in Organic Chemistry 2007; 4 (1) . https://dx.doi.org/10.2174/157017807780037388
DOI https://dx.doi.org/10.2174/157017807780037388 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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