CD93: Recent Advances and Implications in Disease

Title: CD93: Recent Advances and Implications in Disease

Volume: 13 Issue: 3

Author(s): Mallary C. Greenlee-Wacker, Manuel D. Galvan and Suzanne S. Bohlson

Affiliation:

Keywords: CD93, inflammation, innate immunity, Group XIV, adhesion, AA4.1, MMP cleavage site, microarray studies, ischemia, cancer

Abstract: While it has been known for some time that CD93 regulates several processes involved in innate immunity and inflammation including phagocytosis and adhesion, the function of CD93 in disease progression is only now being elucidated. Recent in vivo studies in mice, and genome wide studies in mice and humans, have provided clues about its molecular function. Following a comprehensive review of CD93 expression patterns, this review will focus on recent findings over the last three years that address the putative function of CD93 in inflammation and innate immunity.

Cite this article as:

C. Greenlee-Wacker Mallary, D. Galvan Manuel and S. Bohlson Suzanne, CD93: Recent Advances and Implications in Disease, Current Drug Targets 2012; 13 (3) . https://dx.doi.org/10.2174/138945012799424651