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Anti-Cancer Agents in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1871-5206
ISSN (Online): 1875-5992

Natural Products: Promising Resources for Cancer Drug Discovery

Author(s): Susmita Mondal, Santu Bandyopadhyay, Mrinal K. Ghosh, Sibabrata Mukhopadhyay, Siddhartha Roy and Chitra Mandal

Volume 12, Issue 1, 2012

Page: [49 - 75] Pages: 27

DOI: 10.2174/187152012798764697

Price: $65

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Abstract

Natural products are important sources of anti-cancer lead molecules. Many successful anti-cancer drugs are natural products or their analogues. Many more are under clinical trials. The present review focuses on chemopreventive and anti-cancer activities of polar and non-polar extracts, semi purified fractions and pure molecules from terrestrial plants of India reported between 2005 and 2010 emphasizing possible mechanisms of action of pure molecules.

Keywords: Apoptosis, Chemoprevention, Immunotherapy, Lead molecule, Medicinal plants, CHEMOTHERAPEUTIC, multi-cellular, Neaoplastic cells, Azadirchta Indica, metabolic engineering


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