Abstract
There is increasing concern about the development of diabetes mellitus and associated complications in patients administrating second-generation antipsychotics. Previous reports indicate that the risk of quetiapine, although relatively lower, is not negligible. We report a patient with bipolar disorder who, after treating with low-dose quetiapine, develops newly-onset diabetes and hyperglycemic hyperosmolar state. Clinical manifestations and managements of quetiapine associated diabetes are addressed, and we recommend routine monitoring of serum glucose after initiating quetiapine treatment at any given dose.
Keywords: Quetiapine, diabetes mellitus, hyperglycemic hyperosmolar state, bipolar disorder
Current Drug Safety
Title: Hyperglycemic Hyperosmolar State Associated with Low-Dose Quetiapine Treatment in a Patient with Bipolar Disorder
Volume: 6 Issue: 3
Author(s): Wen-Yin Chen, Chiao-Chicy Chen and Galen C.L. Hung
Affiliation:
Keywords: Quetiapine, diabetes mellitus, hyperglycemic hyperosmolar state, bipolar disorder
Abstract: There is increasing concern about the development of diabetes mellitus and associated complications in patients administrating second-generation antipsychotics. Previous reports indicate that the risk of quetiapine, although relatively lower, is not negligible. We report a patient with bipolar disorder who, after treating with low-dose quetiapine, develops newly-onset diabetes and hyperglycemic hyperosmolar state. Clinical manifestations and managements of quetiapine associated diabetes are addressed, and we recommend routine monitoring of serum glucose after initiating quetiapine treatment at any given dose.
Export Options
About this article
Cite this article as:
Chen Wen-Yin, Chen Chiao-Chicy and C.L. Hung Galen, Hyperglycemic Hyperosmolar State Associated with Low-Dose Quetiapine Treatment in a Patient with Bipolar Disorder, Current Drug Safety 2011; 6 (3) . https://dx.doi.org/10.2174/157488611797579276
DOI https://dx.doi.org/10.2174/157488611797579276 |
Print ISSN 1574-8863 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3911 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Effects of Physical Exercise on Inflammatory Markers of Atherosclerosis
Current Pharmaceutical Design Application of Gene Therapy in Diabetes Care
Infectious Disorders - Drug Targets Glycoprotein Targeting and Other Applications of Lectins in Biotechnology
Current Protein & Peptide Science The Connection Between C-Reactive Protein (CRP) and Diabetic Vasculopathy. Focus on Preclinical Findings
Current Diabetes Reviews Therapeutic Targeting of NLRP3 Inflammasomes by Natural Products and Pharmaceuticals: A Novel Mechanistic Approach for Inflammatory Diseases
Current Medicinal Chemistry A Journey into the World of Targeted Therapy: A Review of Gene Therapy, Stem Cell Therapy, and Cell Reprogramming in Cardiovascular Medicine
Recent Patents on Regenerative Medicine Contribution of Large Animals to Translational Research on Prenatal Programming of Obesity and Associated Diseases
Current Pharmaceutical Biotechnology Glucose Levels and Outcome After Primary Intraventricular Hemorrhage
Current Neurovascular Research Periodontitis and Redox Status: A Review
Current Pharmaceutical Design Liver Fibrosis and Therapeutic Strategies: The Goal for Improving Metabolism
Current Drug Targets Involvement of Cysteine Proteases in Cancer
Current Medicinal Chemistry Cilostazol: A New Drug in the Treatment Intermittent Claudication
Recent Patents on Cardiovascular Drug Discovery Editorial (Thematic Issue: Cell Metabolism and Current Challenges in Drug Research)
Current Pharmaceutical Design Hypertension in Diabetes: Optimal Pharmacotherapy
Cardiovascular & Hematological Agents in Medicinal Chemistry Anti-VEGF Anticancer Drugs: Mind the Hypertension
Recent Advances in Cardiovascular Drug Discovery (Discontinued) Mitochondria as a Therapeutic Target in Alzheimers Disease and Diabetes
CNS & Neurological Disorders - Drug Targets Oxidative Stress in the ICU
Current Nutrition & Food Science Critical Illness in Obstetric Patients: Introduction and Epidemiology
Current Women`s Health Reviews Reproductive Health Indicators and Factors Affecting Menstrual Cycle Pattern among Sudanese Women with Thyroid Dysfunction
Current Women`s Health Reviews New Perspectives of Infections in Cardiovascular Disease
Current Cardiology Reviews